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Table 5 Independent predictors of 30 day mortality in patients with CAL.a

From: Clinical features and predictors of mortality in admitted patients with community- and hospital-acquired legionellosis: A Danish historical cohort study

  CAL  
Predictor variables by category Odds ratio (95% conf. interval) P-value
Demographics   
Age > 65 years 1.3 (0.5-3.7) 0.60
Case associated with travelling to another country 0.4 (0.1-1.4) 0.16
Comorbid illnesses   
Charlson Comorbidity Index ≥ 2 2.8 (0.9-8.5) 0.08
Current smoker 0.7 (0.2-2.0) 0.46
Symptoms   
Self-reported fever 0.7 (0.2-2.3) 0.51
Dyspnoea 1.6 (0.6-4.3) 0.40
Headache 0.1 (0.01-1.03) 0.05
Confusion 3.0 (0.98-9.2) 0.06
Signs   
Normal pulmonary stethoscopy 0.3 (0.05-1.6) 0.16
Laboratory tests   
Lymphocytosis, lymphocyte count >3.5 cells 109/L 33.9 (2.1-553.5) 0.01*
Bilirubin >23 mikromol/L 7.3 (1.6-33.4) 0.01*
Blood urea nitrogen >7.5 mmol/L 1.9 (0.4-8.5) 0.38
Hyponatriemia, sodium <128 mmol/L 0.2 (0.04-0.8) 0.03*
Hypercapnia, PaCO2 >6 kPa 2.4 (0.3-20.4) 0.42
Fibrillatrio atriorum at admission 2.4 (0.6-9.6) 0.22
Treatment   
Treatment with anti-legionella antibiotics < 24 hours from baselineb 0.3 (0.1-1.6) 0.16
Model without symptoms and laboratory tests   
  CAL  
Predictor variables by category Odds ratio (95% conf. interval) P-value
Demographics   
Age > 65 years 2.6 (1.1-5.9) 0.02*
Case associated with travelling to another country 0.5 (0.2-1.3) 0.15
Comorbid illnesses   
Charlson Comorbidity Index ≥ 2 2.7 (1.1-6.5) 0.03*
Current smoker 0.8 (0.3-1.9) 0.56
Signs   
Normal pulmonary stethoscopy 0.3 (0.1-1.2) 0.09
Treatment   
Treatment with anti-legionella antibiotics < 24 hours from baselineb 0.4 (0.1-1.7) 0.21
  1. a For community-acquired cases 30 days from admission. For hospital-acquired cases 30 days from onset of symptoms
  2. b For community-acquired cases time from admission. For hospital-acquired cases time from beginning of symptoms.
  3. * P-level < 0.05 is considered statistically significant