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Table 2 Comparison of laboratory processing times using the GenoType® MTBDRplus assay and the MGIT BACTEC 960 for drug-susceptibility testing.

From: Validation of the GenoType® MTBDRplus assay for detection of MDR-TB in a public health laboratory in Thailand

 

MGIT BACTEC 960

GenoType ® MTBDR plus

Specimen Type

Culture Result to Identification

median days (IQR)

DST Initiation to DST Result

median days (IQR)

Total Time from Culture to DST

median days (IQR)

DNA Extraction to DST Result

median days (IQR)

Total Time from Culture Result to DST

median days (IQR)

Direct Sputum +

15 (12 - 19)

9 (7 - 11)

24.5 (21 - 29)

3 (2 - 5)

N/A

Stored

Isolate

14 (12.5 - 19.5)

9 (7 - 12)

25 (21 - 28.5)

2 (1.5 - 2)

16 (14 - 21)

All Local Specimens

15 (12 - 19)

9 (7 - 11)

25 (21 - 29)

2 (1 - 3)

5 (3 - 9)*

  1. IQR = interquartile range (25th and 75th percentile)
  2. * Pooled for all specimens: for direct sputum AFB+ time from DNA extraction to DST result; for isolates time from culture result to DST result.