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Table 1 Viable organisms/mL before and after one hour exposure to 100 mM Na2SO4, 50 μM H2O2, or 50 μM H2O2 with 50 mU/mL MPO.

From: Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli

 

Initial infectious *units/mL

Infectious *units/mL after 1 hour exposure

 
  

100 mM Na2SO4

50 μM H2O2

50 μM H2O2 with 50 mU/mL MPO

 

HSV-2

1.0 × 105

1.1 × 105

1.2 × 105

1.2 × 105

NS (P = 0.45)

N. gonorrhoeae

1.5 × 107

1.4 × 107

1.3 × 107

1.4 × 107

NS (P = 0.79)

H. ducreyi

1.4 × 107

1.1 × 107

1.5 × 107

1.4 × 107

NS (P = 0.59)

G. vaginalis

8.2 × 107

8.3 × 107

8.3 × 107

8.5 × 107

NS (P = 0.55)

P. bivia

9.2 × 108

9.0 × 105

8.2 × 105

8.8 × 105

NS (P = 0.28)

M. hominis

7.8 × 107

7.7 × 107

7.6 × 107

7.8 × 107

NS (P = 0.39)

M. curtsii

6.1 × 107

4.8 × 107

4.2 × 107

4.4 × 107

NS (P = 0.22)

M. mulieris

8.5 × 107

3.3 × 107

3.4 × 107

3.4 × 107

NS (P = 0.19)

P. anaerobius

7.4 × 108

4.0 × 106

4.3 × 106

4.4 × 106

NS (P = 0.37)

  1. P values from ANOVA comparison of post-exposure means for all three conditions.
  2. * Colony-forming units/mL for bacteria, infected indicator cells/mL for HSV-2.