Figure 4

Expression of PPAR genes in mouse liver. Hepatic gene expression levels of three different peroxisome proliferator-activated receptor genes. Gene expression level was calculated from normalized intensities for six groups of samples. Error bars correspond to standard deviation among the three biological replicates. PPARα is the most highly expressed of the three genes (followed by PPARγ). Furthermore, effect of LPS treatment was assessed for each gene by using a paired t-test (please see details in subsection "Comparison of specific gene expression" under Methods section). The asterisk indicates that LPS treatment causes significant up-regulation (p < 0.05) of PPARα and PPARγ, but not PPARβ/δ.