Figure 2

Agreement with previously published result. Agreement of microarray data with gene expression changes measured by quantitative real-time PCR (qRTPCR) [13]. In both studies the mice were pre-treated with either 100 ng of Ft LVS LPS or equivalent volume of saline (Untreated) 48 hours before infection and sacrificed at 48 hours post-infection. Each number represents the fold-increase in the mRNA levels after infection. While there was rise in the pro-inflammatory cytokine levels post-infection, LPS caused a reduction in expression of these genes (comparable between qRTPCR and microarray; Spearman correlation at p < 0.001).