Table 4 Statistical comparison on the performance of the 3 methods used
From: CMV infection of liver transplant recipients: comparison of antigenemia and molecular biology assays
specificity | Sensitivity a) | PPV | NPV | |||
|---|---|---|---|---|---|---|
Antigenemia pp65 | 67% | 80% | 63% | 49% | ||
globally | CMV Monitor | 63% | 90% | 69% | 57% | |
Without | pp67 mRNA b) | 76% | 85% | 88% | 58% | |
cut-off | Antigenemia pp65 | 62% | - | 30% | 73% | |
Before | ||||||
CMV Monitor | 64% | - | 28% | 74% | ||
treatment | ||||||
pp67 mRNA b) | 79% | - | 60% | 76% | ||
Antigenemia pp65 | 93% | 65% | 94% | 54% | ||
globally | CMV Monitor | 86% | 90% | 89% | 59% | |
With | pp67 mRNA b) | - | - | - | - | |
cut-off | Antigenemia pp65 | 91% | - | 80% | 77% | |
Before | ||||||
CMV Monitor | 87% | - | 57% | 78% | ||
treatment | ||||||
pp67 mRNA b) | - | - | - | - |