Kinetics of CMV determination by antigenemia (squares), CMV monitor (small dots), and CMV pp67 mRNA (circles), in the 5 patients that developed CMV disease. The arrows indicate the onset of CMV disease, and the red rectangles the period of ganciclovir administration. A black R on a red circle indicates a retransplantation surgery. Patient F died at the second retransplantation surgery for reasons not related to CMV disease. The right Y axis was used for qualitative pp67 mRNA assay: P = positive; N = negative.