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  1. Research article

    The prevalence of HIV among adults with pulmonary TB at a population level in Zambia

    Tuberculosis and HIV co-infection is one of the main drivers of poor outcome for both diseases in Zambia. HIV infection has been found to predict TB infection/disease and TB has been reported as a major cause ...

    Pascalina Chanda-Kapata, Nathan Kapata, Eveline Klinkenberg, Martin P. Grobusch and Frank Cobelens

    BMC Infectious Diseases 2017 17:236

    Published on: 29 March 2017

  2. Research article

    Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) colonization as a risk factor for developing ESBL infections in pediatric cardiac surgery patients: “retrospective cohort study”

    Children with cardiac defects need many hospitalizations and repetitive antibiotic therapies, with an increasing risk of colonization with multidrug-resistant bacteria (MDRB) such as extended-spectrum β-lactam...

    Amine Cheikh, Bouchra Belefquih, Younes Chajai, Younes Cheikhaoui, Amine El Hassani and Amina Benouda

    BMC Infectious Diseases 2017 17:237

    Published on: 29 March 2017

  3. Research article

    HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation

    Increased incidence of cardiovascular diseases (CVD) in both HIV infection and type 2 diabetes (T2D) compared to the general population has been described. Little is known about the combined effect of HIV infe...

    Malene Hove-Skovsgaard, Julie Christine Gaardbo, Lilian Kolte, Kamilla Winding, Ingebjørg Seljeflot, Asbjørn Svardal, Rolf Kristian Berge, Jan Gerstoft, Henrik Ullum, Marius Trøseid and Susanne Dam Nielsen

    BMC Infectious Diseases 2017 17:234

    Published on: 29 March 2017

  4. Research article

    Genetic variation in the microsomal triglyceride transfer protein (−493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus

    In chronic hepatitis C, the fibrosis progression rates are extremely variable and can be influenced by factors associated with the host, virus and environment. Among the associated metabolic factors, hepatic s...

    Mariana Cavalheiro Magri, Thamiris Vaz Gago Prata, Caroline Manchiero, Bianca Peixoto Dantas, Celso Carmo Mazza and Fátima Mitiko Tengan

    BMC Infectious Diseases 2017 17:235

    Published on: 29 March 2017

  5. Research article

    Comparison of two commercial broad-range PCR and sequencing assays for identification of bacteria in culture-negative clinical samples

    Culturing has long been the gold standard for detecting aetiologic agents in bacterial infections. In some cases, however, culturing fails to detect the infection. To further investigate culture-negative sampl...

    Camilla Stavnsbjerg, Niels Frimodt-Møller, Claus Moser and Thomas Bjarnsholt

    BMC Infectious Diseases 2017 17:233

    Published on: 27 March 2017

  6. Research article

    Comparison of a novel microcrystalline tyrosine adjuvant with aluminium hydroxide for enhancing vaccination against seasonal influenza

    Vaccination against seasonal influenza strains is recommended for “high risk” patient groups such as infants, elderly and those with respiratory or circulatory diseases. However, efficacy of the trivalent infl...

    M. D Heath, N. J. Swan, A. C. Marriott, N. J. Silman, B. Hallis, C. Prevosto, K. E. Gooch and M. A. Skinner

    BMC Infectious Diseases 2017 17:232

    Published on: 27 March 2017

  7. Research article

    A novel real-time PCR assay for specific detection of Brucella melitensis

    Brucellosis is a zoonosis that occurs worldwide. The disease has been completely eradicated in livestock in Sweden in 1994, and all cases of confirmed human brucellosis are imported into Sweden from other coun...

    Rene Kaden, Sevinc Ferrari, Erik Alm and Tara Wahab

    BMC Infectious Diseases 2017 17:230

    Published on: 24 March 2017

  8. Research article

    Development of selective medium for IMP-type carbapenemase-producing Enterobacteriaceae in stool specimens

    Identification of carbapenemase-producing Enterobacteriaceae (CPE) in faecal specimens is challenging. This fact is particularly critical because low-level carbapenem-resistant organisms such as IMP-producing CPE...

    Norihisa Yamamoto, Ryuji Kawahara, Yukihiro Akeda, Rathina Kumar Shanmugakani, Hisao Yoshida, Hideharu Hagiya, Naohiro Hara, Isao Nishi, Satomi Yukawa, Rumiko Asada, Yumi Sasaki, Kazuhiro Maeda, Noriko Sakamoto, Shigeyuki Hamada and Kazunori Tomono

    BMC Infectious Diseases 2017 17:229

    Published on: 24 March 2017

  9. Research article

    The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study

    Levels of non-neutralising antibodies (AB) to the C5 domain of HIV Env gp120 are inversely related to progression of HIV infection. In this phase I/II clinical study we investigated safety of Vacc-C5, a peptid...

    Kristin Brekke, Maja Sommerfelt, Mats Ökvist, Anne Margarita Dyrhol-Riise and Dag Kvale

    BMC Infectious Diseases 2017 17:228

    Published on: 24 March 2017

  10. Research article

    Drug-induced liver injury from antituberculous treatment: a retrospective study from a large TB centre in the UK

    We describe drug-induced liver injury (DILI) secondary to antituberculous treatment (ATT) in a large tuberculosis (TB) centre in London; we identify the proportion who had risk factors for DILI and the timing ...

    Aula Abbara, Sarah Chitty, Jennifer K. Roe, Rohma Ghani, Simon M. Collin, Andrew Ritchie, Onn Min Kon, John Dzvova, Harriet Davidson, Thomas E. Edwards, Charlotte Hateley, Matthew Routledge, Jim Buckley, Robert N. Davidson and Laurence John

    BMC Infectious Diseases 2017 17:231

    Published on: 24 March 2017

  11. Research article

    Development of a rapid loop-mediated isothermal amplification assay for diagnosis and assessment of cure of Leishmania infection

    Leishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel. A robust, rapid and cost effective diagnostic test ...

    Sandeep Verma, Ruchi Singh, Vanila Sharma, Ram Avtar Bumb, Narendra Singh Negi, V Ramesh and Poonam Salotra

    BMC Infectious Diseases 2017 17:223

    Published on: 23 March 2017

  12. Research article

    Genotype distribution characteristics of multiple human papillomavirus in women from the Taihu River Basin, on the coast of eastern China

    There is limited data on the genotype distribution of human papillomavirus (HPV) in the Taihu River Basin, home to 1.29 million people on the coast of eastern China. This study evaluated the prevalence and gen...

    Jing-fen Lu, Guo-rong Shen, Qiong Li, Xu Chen, Chun-fang Ma and Tong-hua Zhu

    BMC Infectious Diseases 2017 17:226

    Published on: 23 March 2017

  13. Case report

    Leuconostoc mesenteroides periprosthetic knee infection, an unusual fastidious Gram-positive bacteria: a case report

    Periprosthetic joint infections are mainly caused by Gram-positive cocci. Leuconostoc mesenteroides is a rare microorganism mainly causing bloodstream infections. At times, it might be confused with another type ...

    Rafael Franco-Cendejas, Claudia A. Colín-Castro, Melissa Hernández-Durán, Luis E. López-Jácome, Silvestre Ortega-Peña, Guillermo Cerón-González, Samuel Vanegas-Rodríguez, Jaime A. Mondragón-Eguiluz and Eduardo Acosta-Rodríguez

    BMC Infectious Diseases 2017 17:227

    Published on: 23 March 2017

  14. Research article

    Cytomegalovirus infection in HIV-infected versus non-infected infants and HIV disease progression in Cytomegalovirus infected versus non infected infants early treated with cART in the ANRS 12140—Pediacam study in Cameroon

    The outcome of CMV/HIV co-infection in infants treated early with combined antiretroviral therapy (cART) in resource-limited settings has not been described.

    Anfumbom K. W. Kfutwah, Paul Alain T. Ngoupo, Casimir Ledoux Sofeu, Francis Ateba Ndongo, Georgette Guemkam, Suzie Tetang Ndiang, Félicité Owona, Ida Calixte Penda, Patrice Tchendjou, Christine Rouzioux, Josiane Warszawski, Albert Faye and Mathurin Cyrille Tejiokem

    BMC Infectious Diseases 2017 17:224

    Published on: 23 March 2017

  15. Study protocol

    Influenza and respiratory syncytial virus in infants study (IRIS) of hospitalized and non-ill infants aged <1 year in four countries: study design and methods

    This multi-country prospective study of infants aged <1 year aims to assess the frequency of influenza virus and respiratory syncytial virus (RSV) infections associated with hospitalizations, to describe clini...

    Mark G. Thompson, Danielle R. Hunt, Ali K. Arbaji, Artan Simaku, Veronica L. Tallo, Holly M. Biggs, Carolyn Kulb, Aubree Gordon, Ilham Abu Khader, Silvia Bino, Marilla G. Lucero, Eduardo Azziz-Baumgartner, Pat Shifflett, Felix Sanchez, Basima I. Marar, Ilirjana Bakalli…

    BMC Infectious Diseases 2017 17:222

    Published on: 22 March 2017

  16. Research article

    Cytomegalovirus, Epstein-Barr virus and varicella zoster virus infection in the first two years of life: a cohort study in Bradford, UK

    Cytomegalovirus (CMV), Epstein Barr virus (EBV) and varicella-zoster virus (VZV) are common herpesviruses frequently acquired in childhood, which establish persistent, latent infection and are likely to impact...

    Lucy Pembrey, Dagmar Waiblinger, Paul Griffiths, Mauli Patel, Rafaq Azad and John Wright

    BMC Infectious Diseases 2017 17:220

    Published on: 21 March 2017

  17. Research article

    Differential cytokine profiling in Chagasic patients according to their arrhythmogenic-status

    Chagas disease is caused by the protozoan Trypanosoma cruzi and is characterized by heart failure and sudden death. Identifying which factors are involved in evolution and treatment response is actually challengi...

    Héctor Rodríguez-Angulo, Juan Marques, Ivan Mendoza, Marco Villegas, Alfredo Mijares, Núria Gironès and Manuel Fresno

    BMC Infectious Diseases 2017 17:221

    Published on: 21 March 2017

  18. Research article

    Seasonal patterns of dengue fever and associated climate factors in 4 provinces in Vietnam from 1994 to 2013

    In Vietnam, dengue fever (DF) is still a leading cause of hospitalization. The main objective of this study was to evaluate the seasonality and association with climate factors (temperature and precipitation) ...

    Hu Suk Lee, Hung Nguyen-Viet, Vu Sinh Nam, Mihye Lee, Sungho Won, Phuc Pham Duc and Delia Grace

    BMC Infectious Diseases 2017 17:218

    Published on: 20 March 2017

  19. Research article

    Antiviral activity of PHA767491 against human herpes simplex virus in vitro and in vivo

    Herpes simplex virus (HSV) is a common human pathogen that causes a variety of diseases, including oral-labial, genital lesions and life-threatening encephalitis. The antiviral nucleoside analogues such as acy...

    Jue Hou, Zili Zhang, Qiang Huang, Jun Yan, Xiaohu Zhang, Xiaoliang Yu, Guihua Tan, Chunfu Zheng, Feng Xu and Sudan He

    BMC Infectious Diseases 2017 17:217

    Published on: 20 March 2017

  20. Research article

    Multidrug resistant tuberculosis in Ethiopian settings and its association with previous history of anti-tuberculosis treatment: a systematic review and meta-analysis

    Efforts to control the global burden of tuberculosis (TB) have been jeopardized by the rapid evolution of multi-drug resistant Mycobacterium tuberculosis (MTB), which is resistant to at least isoniazid and rifamp...

    Setegn Eshetie, Mucheye Gizachew, Mulat Dagnew, Gemechu Kumera, Haile Woldie, Fekadu Ambaw, Belay Tessema and Feleke Moges

    BMC Infectious Diseases 2017 17:219

    Published on: 20 March 2017

  21. Research article

    Lamivudine/dolutegravir dual therapy in HIV-infected, virologically suppressed patients

    Little is known about the applicability of dual treatments based on integrase inhibitors. We explored the combination of lamivudine + dolutegravir as an option when switching from standard cART in virologicall...

    Franco Maggiolo, Roberto Gulminetti, Layla Pagnucco, Margherita Digaetano, Simone Benatti, Daniela Valenti, Annapaola Callegaro, Diego Ripamonti and Cristina Mussini

    BMC Infectious Diseases 2017 17:215

    Published on: 16 March 2017

  22. Research article

    Imported arboviral infections in Italy, July 2014-October 2015: a National Reference Laboratory report

    Imported cases of infections due to Dengue (DENV) and Chikungunya (CHIKV) viruses and, more recently, Zika virus (ZIKV) are commonly reported among travelers returning from endemic regions. In areas where pote...

    Claudia Fortuna, Maria Elena Remoli, Caterina Rizzo, Eleonora Benedetti, Cristiano Fiorentini, Antonino Bella, Claudio Argentini, Francesca Farchi, Concetta Castilletti, Maria Rosaria Capobianchi, Lorenzo Zammarchi, Alessandro Bartoloni, Nadia Zanchetta, Maria Rita Gismondo, Luca Ceccherini Nelli, Giustina Vitale…

    BMC Infectious Diseases 2017 17:216

    Published on: 16 March 2017

  23. Research article

    Prevalence and Incidence of Smear-Positive Pulmonary Tuberculosis in the Hetosa District of Arsi Zone, Oromia Regional State of Central Ethiopia

    The real burden of smear-positive (PTB+) and bacteriologically confirmed tuberculosis (BCTB) in Ethiopia is not known. Thus, the aim of this community-based study was to measure the prevalence and incidence of...

    ShalloDaba Hamusse, Meaza Demissie, Dejene Teshome, Mohammed Suaudi Hassen and Bernt Lindtjørn

    BMC Infectious Diseases 2017 17:214

    Published on: 16 March 2017

  24. Research article

    Burden and spectrum of bacterial infections among sickle cell disease children living in Cameroon

    Although sickle cell disease (SCD) children are highly susceptible to bacterial infections (BIs), there is a dreadful lack of data related to the burden and spectrum of BIs in sub-Saharan Africa (SSA), the hig...

    Anastasie Nicole Alima Yanda, Jobert Richie N. Nansseu, Hubert Désiré Mbassi Awa, Sandra A. Tatah, Judith Seungue, Charlotte Eposse and Paul Olivier N. Koki

    BMC Infectious Diseases 2017 17:211

    Published on: 15 March 2017

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