Author | Publication year | Sample size1 | S. aureus positive culture (%) | Parenteral (IV) antimicrobial | Days of IV treatment Mean (range) | Oral antimicrobial | Days of oral treatment Mean (range) | Cure rate % (CI) |
---|---|---|---|---|---|---|---|---|
Long Course | ||||||||
Kolyvas2 | 1980 | 5 | 50.03 | Cephradine +/- Ampicillin | 28 (28–28) | Cephradine or Cloxacillin | 18 (14–35) | 100 (67, 100) |
Tetzlaff | 1978 | 18 | 100.0 | Methicillin or Cefazolin | 8 (7–13) | Cephalexin or Penicillin V | 20 (13–42) | 94 (77, 100) |
Bryson | 1979 | 18 | 100.0 | Oxacillin or Methicillin | 7 (5–14) | Dicloxacillin | N/A (28–56) | 100 (89, 100) |
Rodriguez | 1977 | 21 | 90.5 | Clindamycin4 | 25 (21–28) | Clindamycin | 42 (42–42) | 100 (91, 100) |
Prober | 1979 | 22 | 100.0 | Nafcillin or Methicillin | 145 (4–28) | Dicloxacillin | 283 (N/A) | 100 (91, 100) |
Short Course | ||||||||
Kolyvas2 | 1980 | 5 | 50.03 |  | 3 (N/A) | Cephradine or Cloxacillin | 423 (39–60)3 | 100 (67, 100) |
Refass6 | 1989 | 6 | 98.9 | Cloxacillin | N/A (5–6) | Flucloxacillin | N/A (7–200)3 | 100 (72, 100) |
Freij | 1987 | 8 | 100.0 | Imipenem + Cilastatin | 5.5 (4–9) | Cefaclor or Dicloxacillin or Cephalexin or Bacampicillin or Penicillin V | 15 (13–19) | 88 (55, 100) |
Feigin7 | 1975 | 11 | 72.7 | Clindamycin | 6 (3–13) | Clindamycin | 425 (N/A) | 91 (65, 100) |
Geddes8 | 1977 | 18 | 65.03 | Clindamycin | 63 (N/A) | Clindamycin | 903 (N/A) | 94 (77, 100) |
Cole9 | 1982 | 48 | 94.5 | Cloxacillin or Cephalothin | 3 (2–5) | Cloxacillin or Cephalexin | 39 (37–40) | 92 (81, 97) |
Peltola | 1997 | 50 | 100.0 | Cephradine or Cephalothin or Clindamycin | 4 (4–6) | Cefadroxil or Clindamycin | 19 (17–19) | 100 (96, 100) |