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Table 3 Results of multivariable multinomial logistic regression analysis: determinants of zoster vaccine uptake and hesitancy (expressed as delay vs. refusal) (n = 1810)

From: Herpes zoster (HZ) vaccine coverage and confidence in Italy: a Nationwide cross-sectional study, the OBVIOUS project

 

Did get the vaccine

Would get the vaccine

Would not get the vaccine

Characteristic

Predicted probability

Discrete difference (Δ)

Predicted probability

Discrete difference (Δ)

Predicted probability

Discrete difference (Δ)

Estimate

95% CI

Estimate

95% CI

Estimate

95% CI

Gender

         

 Male

10.4%

  

48.2%

  

41.5%

  

 Female†

8.6%

−1.7

−4.0, 0.6

44.6%

−3.6

−7.6, 0.4

46.8%

5.3*

1.6, 9.0

Age group, y

         

  < 65

8.0%

  

51.1%

  

40.9%

  

  ≥ 65

10.2%

2.2

−0.5, 4.9

45.2%

−5.9*

−11.4, −0.5

44.6%

3.7

−1.4, 8.8

NUTS statistical region

         

 Northwestern Italy

8.5%

  

46.3%

  

45.2%

  

 Northeastern Italy

15.6%

7.1*

3.3, 10.9

37.2%

−9.2*

−15.0, −3.3

47.3%

2.0

−3.4, 7.5

 Central Italy

6.9%

−1.5

−5.1, 2.0

49.9%

3.6

−2.2, 9.5

43.1%

−2.1

−7.2, 3.1

 Southern Italy

7.0%

−1.4

−4.8, 1.9

51.4%

5.0

−0.6, 10.7

41.6%

−3.6

−8.6, 1.4

 Insular Italy

4.0%

−4.4*

−8.3, −0.6

56.4%

10.1*

2.7, 17.5

39.5%

−5.7

−12.4, 1.0

Degree of urbanisation‡

         

 City

9.0%

  

47.7%

  

43.3%

  

 Town or suburb

9.0%

0.0

−2.5, 2.4

47.0%

−0.7

−5.0, 3.6

44.0%

0.7

−3.2, 4.6

 Rural area

13.0%

4.0*

0.0, 8.0

42.8%

−5.0

−11.3, 1.4

44.2%

0.9

−4.9, 6.7

Educational attainment

         

 Academic/Post-graduate degree

11.2%

  

50.4%

  

38.4%

  

 High school diploma

9.4%

−1.8

−4.7, 1.0

45.6%

−4.8

−9.6, 0.0

45.0%

6.6*

2.2, 11.1

 Less than high school diploma

7.8%

−3.4*

−6.9, 0.0

46.2%

−4.2

−10.5, 2.0

46.0%

7.7*

1.9, 13.5

Diabetes

         

 No

8.5%

  

47.5%

  

44.0%

  

 Yes

12.6%

4.2*

1.0, 7.3

44.5%

−3.0

−8.3, 2.3

42.9%

−1.1

−6.0, 3.7

Pneumopathy

         

 No

9.3%

  

47.0%

  

43.7%

  

 Yes

12.4%

3.1

−0.8, 7.1

43.7%

−3.3

−9.7, 3.0

43.9%

0.2

−5.7, 6.0

Cardiopathy

         

 No

9.2%

  

45.8%

  

45.0%

  

 Yes

11.4%

2.2

−1.1, 5.4

50.1%

4.3

− 1.1, 9.7

38.5%

−6.5*

−11.4, − 1.6

Worry about shingles

         

 Very/Quite worried

12.4%

  

70.9%

  

16.7%

  

 A little worried

8.6%

−3.8*

−6.8, −0.7

48.8%

−22.1*

−27.1, −17.1

42.6%

25.9*

21.4, 30.4

 Not worried

8.6%

−3.8*

−7.2, −0.3

24.1%

−46.7*

−52.3, −41.2

67.2%

50.5*

45.2, 55.8

Perception of vaccine safety

         

 Very safe

13.6%

  

61.2%

  

25.2%

  

 Quite safe

8.6%

−5.0*

−8.9, −1.0

49.5%

−11.7*

−18.1, −5.3

41.9%

16.7*

11.0, 22.3

 Quite/Very unsafe

8.3%

−5.2

−10.9, 0.4

17.8%

−43.5*

−51.7, −35.2

73.9%

48.7*

41.0, 56.4

Dear ones’ views on vaccination in general

         

 Very favorable

8.9%

  

55.3%

  

35.9%

  

 Favorable

9.4%

0.5

−2.3, 3.3

48.5%

−6.7*

−12.0, − 1.5

42.1%

6.2*

1.3, 11.1

 Quite favorable

10.8%

2.0

−1.4, 5.3

38.7%

−16.5*

−22.1, −10.9

50.5%

14.6*

9.4, 19.8

 Quite to very unfavorable

12.4%

3.5

−1.3, 8.4

35.8%

−19.5*

−27.1, −11.9

51.8%

15.9*

9.1, 22.8

Awareness of having priority for vaccination

         

 Yes

20.1%

  

51.2%

  

28.7%

  

 No

5.2%

−14.9*

−19.7, −10.2

40.1%

−11.0*

−18.1, −4.0

54.7%

26.0*

19.5, 32.5

 Don’t know

3.4%

−16.7*

−20.6, − 12.9

49.9%

−1.2

−6.4, 3.9

46.7%

18.0*

13.3, 22.7

Perceived ease of access to get the vaccine

         

 Very easy

13.7%

  

41.0%

  

45.3%

  

 Quite easy

8.3%

−5.4*

−9.2, −1.6

46.8%

5.8

−0.7, 12.2

44.9%

−0.4

−6.4, 5.7

 Quite/Very difficult

7.9%

−5.8*

−10.3, − 1.4

52.0%

11.0*

3.5, 18.4

40.1%

−5.2

−12.0, 1.7

  1. *P-value ≤0.05, that is, Δ significantly ≠ 0
  2. †Including non-binary persons
  3. ‡According to the Eurostat Degree of Urbanization (DEGURBA) classification system
  4. NUTS Nomenclature of Territorial Units for Statistics