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Table 2 The difference of clinical characteristics based on different duration of hospitalization

From: Liver injury and prolonged hospitalization as indicators of severity in patients with adenovirus infections

Parameter

≤ 7 days

8–14 days

> 14 days

p1 value

No.(%)

No.(%)

p2 value

No.(%)

p3 value

Total No.

651

349

151

 

Age

644

345

< 0.001

150

< 0.001

< 0.001

 < 3 m

3(0.46)

6(1.74)

 

3(2.00)

  

 3 m−1y

72(11.18)

102(29.56)

 

64(42.67)

  

 1−2y

125(19.41)

93(26.96)

 

44(29.33)

  

 2−5y

327(50.78)

111(32.17)

 

33(22.00)

  

 ≥ 5y

117(18.17)

33(9.57)

 

6(4.00)

  

X-ray

439

305

< 0.001

148

< 0.001

< 0.001

 Normal

201(45.78)

47(15.41)

 

5(3.38)

  

 aOne side

64(14.58)

53(17.38)

 

6(4.05)

  

 bBoth side

174(39.64)

205(67.21)

 

137(92.57)

  

High fever(≥ 39°C)

651

349

< 0.001

151

< 0.001

< 0.001

297(45.62)

256(73.35)

 

127(84.11)

  

Blood system

      

Abnormal RBC count

150(24.47)

98(28.74)

0.423

49(35.58)

0.022

0.064

Abnormal Hb

174(28.20)

118(34.50)

0.309

57(44.88)

0.013

0.041

Abnormal WBC count

187(30.21)

114(33.33)

0.648

57(47.24)

0.013

0.029

Abnormal Neutrophil(%)

214(34.63)

168(49.12)

0.045

83(65.87)

< 0.001

< 0.001

Abnormal lymphocyte(%)

150(24.35)

94(27.49)

0.626

63(50.50)

< 0.001

< 0.001

Abnormal CRP

571(98.45)

332(98.52)

0.561

122(97.60)

1

0.816

Liver function

      

Abnormal AST

115(18.91)

133(39.12)

< 0.001

81(54.36)

< 0.001

< 0.001

Abnormal ALT

58(9.54)

37(10.88)

0.509

35(23.49)

< 0.001

< 0.001

Kidney function

      

Abnormal Creatinine

2(0.33)

4(1.18)

0.113

1(0.67)

0.553

0.288

Abnormal Urea

50(8.20)

34(10.00)

0.348

15(10.00)

0.479

0.583

Abnormal Albumin

126(20.59)

112(32.75)

< 0.001

79(52.67)

< 0.001

< 0.001

Myocardial injury

      

Abnormal TnI

14(2.35)

19(5.78)

0.149

28(24.56)

< 0.001

< 0.001

Abnormal CKMB

49(8.24)

30(9.09)

0.800

16(14.04)

0.175

0.328

Abnormal BNP

6(1.76)

5(2.87)

0.651

6(8.96)

0.030

0.040

Blood gas analysis

      

Abnormal PH

66(47.48)

49(38.28)

0.198

50(46.73)

1.000

0.334

Abnormal PaO2

102(73.38)

88(68.75)

0.533

91(85.05)

0.037

0.023

Abnormal SPO2

21(15.11)

17(13.28)

0.684

31(28.97)

0.017

0.007

  1. Note: a.One side, indicates that infiltration only occurs in the left lung lobe or right lung lobe; b.Both side, indicates that infiltration occurs in the both left and right lung lobe; p1, comparison among three groups. p2 and p3, compared to the group with duration of hospitalization ≤ 7 days. Abbre. NO., number; m, month; y, year; RBC, red blood cell; Hb, hemoglobin; WBC, white blood cell; CRP, C-reactive protein; AST, Aspartate aminotransferase; ALT, glutamic-pyruvic transaminase; TnI, troponin; CKMB, creatine kinase isoenzyme; BNP, B-type brain natriuretic peptide; PaO2, arterial oxygen partial pressure; SPO2, oxygen saturation of blood. p value was calculated by Pearson chi-square test