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Table 4 Cutoff values of blood composite ratios in predicting microfilaridermia

From: Association of haemato-biochemical indices and blood composite ratios with microfilaridermia in Onchocerciasis patients

Parameter

Cut-off

Sensitivity (95% CI)

Specificity (95% CI)

Accuracy (95% CI)

PPV (95% CI)

NPV (95% CI)

p-Value

Eosinophil [Abs]

> 0.415

50.5 [40.6–60.4]

88.2 [72.6–96.7]

59.7 [51.1–67.9]

93.0 [83.8–97.1]

36.6 [31.5–42.0]

< 0.001

Basophil [Abs]

> 0.025

63.8 [53.9–73.0]

67.7 [49.5–82.6]

64.8 [56.2–72.7]

85.9 [78.6–91.0]

37.7 [30.0–46.1]

0.001

ENR x10

> 2.265

50.5 [40.6–60.4]

91.2 [76.3–98.1]

60.4 [51.8–68.6]

94.6 [85.5–98.2]

37.4 [32.4–42.6]

< 0.001

EMR

> 0.395

79.1 [70.0–86.4]

61.8 [43.6–77.8]

74.8 [66.8–81.8]

86.5 [80.5–90.8]

48.8 [37.7–60.1]

< 0.001

EBR

> 14.25

51.4 [41.5–61.3]

85.3 [68.9–95.1]

59.7 [51.1–67.9]

91.5 [82.5–96.1]

36.3 [30.9–42.0]

< 0.001

ELR x10

> 1.160

63.8 [53.9–73.0]

70.6 [52.5–84.9]

65.5 [56.9–73.3]

87.0 [79.6–92.0]

38.5 [31.1–46.9]

< 0.001

  1. PPV; positive predictive value, NPV; negative predictive value, CI; confidence interval, abs; absolute count, EBR: eosinophil-to-basophil ratio; EMR: eosinophil-to-monocyte ratio; NLR: neutrophil-to-lymphocyte ratio; ELR: eosinophil-to-lymphocyte ratio. The Chi-square test was used for all analyses. p-value less than 0.05 was considered statistically significant