Association of haemato-biochemical indices and blood composite ratios with microfilaridermia in Onchocerciasis patients

Debrah, Linda Batsa; Gyasi, Charles; Ahiadorme, Monica; Rahamani, Abu Abudu; Opoku, Vera Serwaa; Obeng, Prince; Osei-Mensah, Jubin; Obeng, Michael Agyemang; Mensah, Derrick Adu; Debrah, Alexander Yaw

doi:10.1186/s12879-024-09278-0

Table 2 Haematological and biochemical ranges and abnormalities of study participants

From: Association of haemato-biochemical indices and blood composite ratios with microfilaridermia in Onchocerciasis patients

Variable	unit	Classification	a-Microfilaridermics (MF-, n = 34)	Microfilaridermics (MF+, n = 105)	Total n (%)	Reference range
RBC	x10⁶/L	Normal	31 (91.2)	98 (93.3)	129 (92.8)	2.50–5.50
RBC	x10⁶/L	Abnormal	3 (8.8)	7 (6.7)	10 (7.2)	2.50–5.50
HGB	g/dL	Normal	34 (100.0)	105 (100.0)	139 (100.0)	8.0–17.0
HGB	g/dL	Abnormal	0 (0.0)	0 (0.0)	0 (0.0)	8.0–17.0
HCT	%	Normal	34 (100.0)	105 (100.0)	139 (100.0)	26.0–50.0
HCT	%	Abnormal	0 (0.0)	0 (0.0)	0 (0.0)	26.0–50.0
PLT	x10³/L	Normal	33 (97.1)	104 (99.0)	137 (98.6)	50–400
PLT	x10³/L	Abnormal	1 (2.9)	1 (1.0)	2 (1.4)	50–400
Total WBC	x10⁹/L	Normal	34 (100.0)	104 (99.0)	138 (99.3)	3.00–15.00
Total WBC	x10⁹/L	Abnormal	0 (0.0)	1 (1.0)	1 (0.7)	3.00–15.00
Neutrophil Abs	x10⁹/L	Normal	34 (100.0)	104 (99.0)	138 (99.3)	1.50–7.00
Neutrophil Abs	x10⁹/L	Abnormal	0 (0.0)	1 (1.0)	1 (0.7)	1.50–7.00
Lymphocyte Abs	x10⁹/L	Normal	33 (97.1)	98 (93.3)	131 (94.2)	1.00–3.70
Lymphocyte Abs	x10⁹/L	Abnormal	1 (2.9)	7 (6.7)	8 (5.8)	1.00–3.70
Monocyte Abs	x10⁹/L	Normal	34 (100.0)	95 (90.5)	129 (92.8)	0.00–0.70
Monocyte Abs	x10⁹/L	Abnormal	0 (0.0)	10 (9.5)	10 (7.2)	0.00–0.70
Eosinophil Abs	x10⁹/L	Normal	29 (85.3)	51 (48.6)	80 (57.6)	0.00–0.40
Eosinophil Abs	x10⁹/L	Abnormal	5 (14.7)	54 (51.4)	59 (42.4)	0.00–0.40
Basophil Abs	x10⁹/L	Normal	34 (100.0)	105 (100.0)	139 (100.0)	0.00–0.10
Basophil Abs	x10⁹/L	Abnormal	0 (0.0)	0 (0.0)	0 (0.0)	0.00–0.10
Neutrophil %	%	Normal	34 (100.0)	104 (99.0)	138 (99.3)	37.0–72.0
Neutrophil %	%	Abnormal	0 (0.0)	1 (1.0)	1 (0.7)	37.0–72.0
Lymphocyte %	%	Normal	25 (73.5)	86 (81.9)	111 (79.9)	20.0–50.0
Lymphocyte %	%	Abnormal	9 (26.5)	19 (18.1)	28 (20.1)	20.0–50.0
Monocyte %	%	Normal	33 (97.1)	99 (94.3)	132 (95.0)	0.0–14.0
Monocyte %	%	Abnormal	1 (2.9)	6 (5.7)	7 (5.0)	0.0–14.0
Eosinophil %	%	Normal	24 (70.6)	44 (41.9)	68 (48.9)	0.0 − 6.0
Eosinophil %	%	Abnormal	10 (29.4)	61 (58.1)	71 (51.1)	0.0 − 6.0
Basophil %	%	Normal	34 (100.0)	102 (97.1)	136 (97.8)	0.0–1.0
Basophil %	%	Abnormal	0 (0.0)	3 (2.9)	3 (2.2)	0.0–1.0
ALT	U/L	Normal	30 (88.2)	99 (94.3)	129 (92.8)	0.0–40.0
ALT	U/L	Abnormal	4 (11.8)	6 (5.7)	10 (7.2)	0.0–40.0
AST	U/L	Normal	32 (94.1)	95 (90.5)	127 (91.4)	0.0–40.0
AST	U/L	Abnormal	2 (5.9)	10 (9.5)	12 (8.6)	0.0–40.0
GGT	U/L	Normal	30 (88.2)	97 (92.4)	127 (91.4)	0.0–55.0
GGT	U/L	Abnormal	4 (11.8)	8 (7.6)	12 (8.6)	0.0–55.0
Creatinine	µmol/L	Normal	31 (91.2)	102 (97.1)	133 (95.7)	53.0–124.0
Creatinine	µmol/L	Abnormal	3 (8.8)	3 (2.9)	6 (4.3)	53.0–124.0
eGFR	mL/min/1.73m2	Normal	17 (50.0)	66 (62.9)	83 (59.7)	> 90.00
eGFR	mL/min/1.73m2	Abnormal	17 (50.0)	39 (37.1)	56 (40.3)	> 90.00

RBC; red blood cell count, HGB; haemoglobin concentration, PLT; platelet count, WBC; white blood cell count, ALT; alanine transaminase, AST; aspartate transaminase, GGT; gamma-glutamyl transferase, eGFR; estimated glomerular filtration rate

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