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Table 2 Acceptability questionnaires in PWH and PrEP users

From: Injectable long acting antiretroviral for HIV treatment and prevention: perspectives of potential users

Variable

HIV

N = 100

Prep

N = 100

P

Would accept LAA every other month, n (%)

74 (74)

89 (89)

0.001

Perceived advantages

   

 Stop taking cARTa-treatment every day, n (%)

73 (73)

73 (73)

 > 0.99

 Being certain of efficacy for a period of time, n (%)

42 (42)

51 (51)

0.26

 Being certain not to forget cART-treatment, n (%)

39 (39)

68 (68)

 < 0.0001

 Hiding that I take cART-treatment, n (%)

0 (0)

7 (7)

0.014

 No need to think of treatment every day, n (%)

28 (28)

62 (62)

 < 0.0001

 Forget the disease, n (%)

19 (19)

 Other, n (%)

11 (11)

0 (0)

0.0007

 None, n (%)

11 (11)

0 (0)

0.0007

Perceived drawbacks

   

 Loss of freedom, n (%)

6 (6)

30 (30)

 < 0.0001

 Fear of adverse effects, n (%)

29 (29)

47 (47)

0.013

 Fear of injections, n (%)

14 (14)

19 (19)

0.45

 Fear of being treated as a Guinea pig, n (%)

17 (17)

23 (23)

0.38

 It would not change anything, n (%)

9 (9)

8 (8)

 > 0.99

 Already taking other treatments, n (%)

7 (7)

1 (1)

0.065

 Too much a constraint, n (%)

21 (21)

0 (0)

 < 0.0001

 Other, n (%)

6 (6)

0 (0)

0.029

 None, n (%)

29 (29)

22 (22)

0.33

What do you feel about coming every other month?

   

 Beneficial because more follow-up, n (%)

23 (23)

28 (28)

0.52

 I don't like the idea of going more often to the hospital, n (%)

34 (34)

21 (21)

0.057

 I don't care, n (%)

42 (42)

53 (53)

0.16

About an injectable treatment?

   

 Do not wish to change my treatment, n (%)

23 (23)

12 (12)

0.062

 Accepts both injections and hospital visits, n (%)

35 (35)

58 (58)

0.002

 Accepts injections but not hospital visits, n (%)

29 (29)

21 (21)

0.25

 Accepts injections but fears adverse effects, n (%)

18 (18)

19 (19)

 > 0.99

 Would like to switch to injections at specific times, n (%)

27 (27)

29 (29)

0.87

Would you accept participating to a clinical trial?

   

 Would not participate, n (%)

28 (28)

31 (31)

0.76

 Would accept injections at the hospital, n (%)

34 (34)

36 (36)

0.88

 Could accept injections if self-administered, n (%)

19 (19)

7 (7)

0.019

  1. aART: combined antiretroviral therapies