Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection

Table 3 Multiple Linear Regression Models with TMAO as Dependent Variable

Characteristics	Standardized β coefficient	P
Age	0.233	0.10
Gender	0.079	0.58
Smoking	0.123	0.39
sCD14	0.381	0.008
Model with additional adjustment for each of the following variables
CD4⁺ T-cell count	0.379	0.010
Viral load	0.452	0.003
hsCRP	0.304	0.045
LPS	0.384	0.009

Multivariate linear regression analyses with TMAO as dependent variable. Standardized β coefficients for TMAO are given after adjustment for a fifth variable. sCD14, soluble CD14, TMAO, Trimethylamine-N-oxide

ISSN: 1471-2334