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Table 2 Distribution of DENV-4 cases analyzed in the State of Rio de Janeiro, Brazil, from 2011 to 2013 and confirmed according to the routine laboratorial diagnosis methodologies used

From: Dengue type 4 in Rio de Janeiro, Brazil: case characterization following its introduction in an endemic region

Methodology/Year

Positive cases/Total analyzed (%)

p value

Virus isolation

298/612 (48.7)

Ā 

RT-PCR

704/705 (99.8)

Ā 

MAC-ELISA

104/264 (39.4)

Ā 

NS1 Capture ELISA

231/557 (41.5)

0.001

NS1 Capture ELISA after dissociation

488/557 (87.6)