Clinical diagnostic value of viable Schistosoma japonicum eggs detected in host tissues

BMC Infectious Diseases

Table 7 The amount of S. japonicum egg mRNA and the positive rate of different types of eggs tested in intestinal mucosal biopsies from 45 patients determined by real time PCR

	CM cases	CME cases	SVE cases	Cases with mainly PDE	Only CDE cases
Tested Patients(n)	10	35	10	16	9
S. japonicum egg mRNA(M + SD)	0.50 ±0.17	135.37 ±189.62	357.04 ±234.84	69.26 ±62.13	19.17 ±11.06
*Positive patients(n)	0	18	10	8	0
Positivity rate (%)	0.00	51.43	100.00	50.00	0.00

CM (colonic mucosal without eggs), CME (colonic mucosal with eggs), SVE (suspected viable eggs in colonic mucosal), PDE (partially degraded eggs in colonic mucosal), CDE (completely degraded eggs in colonic mucosal)
* Content of positivity: the mRNA content of a sample with eggs was double that of viable eggs (20.9 ± 3.56 copies)

ISSN: 1471-2334