Study | Methods | Sample Size (at baseline) | % Women | % Taking combination ART | Participants (at study completion) | Withdrawal Rate |
---|---|---|---|---|---|---|
Agin (2001) [35] | Randomized combined PRE and whey protein vs whey protein alone vs PRE alone [3 groups] | 43 (with wasting) | 100% | Unknown | 30 | 13/43 (30%) |
Agostini (2009) [25]a, b | Randomized combined AERÂ +Â PRE vs diet and aerobic exercise recommendation alone (no exercise) [2 groups] | 76 | 39% | 100% | 70 | 6/76 (8%) |
Balasubramanyam (2011) [26]a, b | Randomized trial with five groups. In this review we compared diet and exercise (lifestyle change) vs usual care (no exercise) [2 groups] | 191 (with dyslipidemia) | 13% | 100% | 128 (68 participants in the 2 comparison groups of interest) | 63/191 (33%) |
Bhasin (2000) [36] | Randomized PRE vs PREÂ +Â testosterone vs testosterone only vs no exercise [4 groups] | 61 (with involuntary weight loss and low testosterone) | 0% | 100% taking ARVs (unclear whether it was cART) | 49 | 12/61 (20%) |
Dolan (2006) [37]b | Randomized constant ARE +PRE vs no exercise [2 groups] | 40 (with self-reported and physical evidence of changes in fat distribution) | 100% | 82% taking ARVs (unclear whether it was cART) | 38 | 2/40 (5%) |
Driscoll (2004a) [38]b | Randomized combined AERÂ +Â PRE and metformin vs metformin alone [2 groups] | 37 (evidence of fat redistribution and hyperinsulinemia) | 20% | 100% | 25 | 12/37 (32%) |
Farinatti (2010) [27]a, b | Randomized constant AERÂ +Â PRE exercise vs no exercise [2 groups] | 27 | Not reported | 100% | 27 | 0/27 (0%) |
Fitch (2012) [28]a, b | Randomized constant AERÂ +Â PRE exercise (LSM) vs AERÂ +Â PRE exercise + metformin vs no LSM and metformin alone vs versus no exercise (no LSM or metformin) [4 groups] | 50 (with metabolic syndrome) | 24% | 100% | 36 | 14/50 (28%) |
Grinspoon (2000) [39]b | Randomized PREÂ +Â AER vs PREÂ +Â AER and testosterone vs testosterone alone vs no exercise [4 groups] | 54 (with AIDS-related wasting) | 0% | 72% | 43 | 11/54 (20%) [4/26 (15%) from the 2 groups of interest] |
Lindegaard (2008) [29]a, b | Randomized AER vs PRE [2 groups] | 20 (with dyslipidemia, lipodystrophy) | 0% | 100% | 18 | 2/20 (10%) |
Lox (1995) [40]b | Randomized constant AER vs PRE vs no exercise [3 groups]c | 22 (aerobic and control groups only) | 0% | 100% (taking some form of ARV therapy that may or may not have been in combination) | 21 | 1/22 (4%) |
Ogalha (2011) [30]a, b | Randomized AER+ PREÂ +Â nutrition counseling vs nutrition counseling alone [2 groups] | 70 (lipodystrophy in 54% of participants) | 46% | 100% | 63 | 7/70 (10%) |
Perez-Moreno (2007) [31]a, b | Randomized constant AER+ PRE vs no exercise [2 groups] | 27 (prison inmates living with Hepatitis C co-infection) | 0% | 10% | 19 | 8/27 (30%) |
Rigbsy (1992) [41] | Randomized constant AER+ PRE vs no exercise (counselling) [2 groups] | 45 (37 HIV+) | 0% | Not reported | 31 (24 HIV+) | 13/37 (35%) |
Sakkas (2009) [32]a | Randomized PRE+ creatine vs PRE alone [2 groups] | 40 | 0% | 75% | 33 | 7/40 (18%) |
Sattler (1999) [42] | Randomized PRE+ testosterone vs testosterone only [2 groups] | 33 | 0% | 80% | 30 | 3/33 (9%) |
Shevitz (2005) [43] | Randomized combined PRE+ nutrition + oxandrolone vs nutrition + oxandrolone vs nutrition alone [3 groups] | 50 (with wasting) | 30% | 80% | 47 | 3/50 (6%) |
Spence (1990) [44] | Randomized PRE vs no exercise (control) [2 groups] | 24 | 0% | 100% taking AZT | NR | Unknown |
Tiozzo (2011) [33]a, b | Randomized constant AERÂ +Â PRE vs no exercise (control) [2 groups] | 37 | 39% | 100% | 23 | 14/37 (38%) |
Yarasheski (2011) [34]a, b | Randomized constant AER+ PRE+ pioglitazone vs pioglitazone only [2 groups] | 44 (with insulin resistance, impaired glucose intolerance and central adiposity) | 13% | 100% | 39 | 5/44 (11%) |