Table 2 Identification of Streptococcus equi subsp. zooepidemicus ST 364 putative virulence factors by proteomic analysis
From: Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer
Protein name | Gene name(s) | Relative cellular abundancea | Relative quantificationb (log2 LFQ intensity) | |
|---|---|---|---|---|
Median | Standard deviation | |||
Fibronectin/fibrinogen-binding protein | fbp | + | 21.7 | 0.1 |
Beta-N-acetylglucosaminidase/ Hyaluronidase | hylZ | + | 20.7 | 0.4 |
M-like protein | mlpZ | ++ | 24.9 | 0.2 |
Secreted antigen GbpB/SagA/PcsB, putative peptidoglycan hydrolase | Sez_0018 | + | 21.0 | 0.1 |
Streptolysin S biosynthesis protein SagB | sagB | + | 20.7 | 0.1 |
Streptolysin S biosynthesis protein SagC | sagC | ++ | 26.1 | 0.1 |
Streptolysin S biosynthesis protein SagD | sagD | ++ | 25.4 | 0.1 |
Streptolysin S export protein SagG | sagG | ++ | 26.8 | 0.1 |
Streptolysin S export transmembrane permease SagH | sagH | + | 23.1 | 0.1 |
Streptolysin S export transmembrane permease SagI | sagI | + | 22.3 | 0.1 |
Serine endopeptidase, lactocepin, interleukin-8 protease-like protein | scpC/cepA | ++ | 25.1 | 0.1 |
Streptodornase type B | sdzB | ++ | 26.6 | 0.2 |
Streptodornase type D | sdzD | ++ | 24.1 | 0.1 |
Streptokinase; Skc_1 protein | skc_1 | ++ | 24.3 | 0.1 |
Uncharacterized streptokinase-like protein; Skc_2 protein | skc_2 | + | 23.7 | 0.1 |
Protective antigen-like protein, fibrinogen-and Ig-binding protein | spaZ | + | 23.7 | 0.1 |
Antiphagocytic cell surface-anchored fibrinogen-and IgG Fc-binding protein SzM | szm | +++ | 31.4 | 0.1 |
Fibrinogen-binding cell surface-anchored protein SzP | szp | + | 22.0 | 0.3 |
Elongation factor Tuc | tuf | +++ | 31.9 | 0.1 |