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Table 2 Sample size calculation

From: Treatment efficacy of azithromycin 1 g single dose versus doxycycline 100 mg twice daily for 7 days for the treatment of rectal chlamydia among men who have sex with men – a double-blind randomised controlled trial protocol

Doxycycline cure

98% cure

96% cure

Power

80%

90%

80%

90%

Difference to detecta

 %

538

720

762

1018

 6%

412

552

560

756

 7%

332

442

444

592

  1. aAssumes azithromycin microbial cure will be 5–7% lower. Sample size calculation assumes 5% significance
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BMC Infectious Diseases

ISSN: 1471-2334

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