Table 1 Characteristics of IPD patients in 10 prefectures in Japan (n = 291) from April 2013 to March 2015
Variable | n/Na (%) |
|---|---|
Female | 107/291 (37) |
Median age; years (IQR) | 70 (61-81) |
Age group | |
15–39 years | 15/291 (5) |
40–64 years | 86/291 (30) |
≧65 years | 190 (65) |
BMI | |
Normal or Healthy Weight (18.5 – 24.9) | 139/248 (56) |
Overweight (25.0 and Above) | 41/248 (17) |
Underweight (Below 18.5) | 68/248 (27) |
Smoking history | 132/256 (52) |
Alcohol abuse | 39/257 (15) |
Preceding influenza | 11/192 (6) |
Vaccination history of PPSV23 | 16/231 (7) |
Comorbidities | 202/281 (72) |
Chronic pulmonary disease | 24/281 (9) |
Chronic heart disease | 19/281 (7) |
Chronic liver disease | 19/281 (7) |
Chronic kidney disease | 17/281 (6) |
Diabetes mellitus | 34/281 (12) |
Immunocompromised status | 107/281 (38) |
Hyposplenia/asplenia | 14/271 (5) |
Autoimmune disease | 33/281 (12) |
Corticosteroid therapy | 26/281 (9) |
Malignancy | 56/281 (20) |
Solid cancer | 37/281 (13) |
Hematologic cancer | 17/281 (6) |
Anti-cancer agent | 22/281 (8) |
Clinical presentation | |
Bacteremia without any focus | 47/291 (16) |
Meningitis | 46/291 (16) |
Bacteremic pneumonia | 173/291 (59) |
Othersb | 25/291 (9) |
Serotype | |
PCV13 type | 135/291 (46) |
PPSV23 type | 191/291 (66) |
Outcomec | |
Fatal | 57/291 (20) |