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Table 5 Incidence rate, univariate and multivariate analysis among IPT completed, in-completed and non- exposed patients in public health facilities of Addis Ababa, during 2007-June 2012

From: Effectiveness of isoniazid preventative therapy in reducing incidence of active tuberculosis among people living with HIV/AIDS in public health facilities of Addis Ababa, Ethiopia: a historical cohort study

Patient profile

Event/P/Y

IR/100P-Y

Crude IRR (95% CI)

Adjusted IRR(95% CI)

Over all

277/4106

6.7

  

IPT completed

7/33.3

0.21

0.03(0.01–0.06)

0.04(0.05–0.07)

IPT in-completed

8/7.8

0.86

0.84(0.36–1.33)

0.89(0.49–1.76)

IPT non-exposed

262/36.49

7.18

1

1

Sex

 Male

138/2822.1

4.89

1.80(1.42–2.28)

1.59(1.20–2.12)

 Female

139/5129.2

2.71

1

1

Age group in year

 <30

103/3038.3

3.39

1

1

 30–39

87/2628.4

3.31

0.98(0.73–1.29)

0.82(0.61–1.11)

 40–49

61/1644.2

3.71

1.09(0.79–1.49)

1.04(0.74–1.47)

 >49

26/637.3

4.08

1.201(0.77–1.82)

1.55(0.95–2.44)

Residence area

 Living out of Addis Ababa

4/135.1

2.96

0.85(0.26–1.99)

0.29(0.09–0.73)

 Living in Addis Ababa

273/7800

3.50

1

1

Religion

 Orthodox

231/6243.2

3.70

0.63(0.20–3.82)

0.29(0.08–1.86)

 Muslim

19/892

2.13

0.36(0.11–2.28)

0.17(0.04–1.13)

 Protestant

25/778.8

3.21

0.55(0.16–3.40)

0.32(0.09–2.12)

 Others*

11/187.7

5.86

1

1

Marital status

 Married

127/3547.5

3.58

0.82(0.46–1.68)

1.22(0.66–2.51)

 Single

72/1889.8

3.81

0.88(0.48–1.81)

1.18(0.63–2.48)

 Widowed

33/1284

2.57

0.59(0.30–1.27)

0.81(0.40–1.76)

 Divorced

35/997.2

3.51

0.81(0.45–1.72)

1.05(0.53–2.27)

 Separated

10/229.9

4.35

1

1

Employment

 Self employed

87/3782.6

2.30

0.03(0.01–0.19)

0.02(0.01–0.12)

 Private Employed

58/1418.1

4.09

0.06(0.02–0.35)

0.03(0.01–0.16)

 Government employed

62/1324.8

4.68

0.07(0.02–0.40)

0.03(0.01–0.19)

 Student

3/66.5

4.51

0.06(0.01–0.48)

0.01(0.002–0.101)

 Non- employed

65/1354.2

4.80

1

1

Educational level

 None educated

42/1707.3

2.46

0.65(0.35–1.33)

1.25(0.62–2.70)

 Primary Completed

106/3028.6

3.50

0.93(0.52–1.83)

1.69(0.89–3.49)

 Secondary Completed

118/2920.8

4.04

1.07(0.60–2.10)

1.76(0.97–3.55)

 Tertiary completed

11/291

3.78

1

1

House Hold size/room no.

  

0.99(0.89–1.09)

0.98(0.88–1.07)

Baseline WHO stage of HIV/AIDS

 Stage 1 & 2

45/4545.5

0.99

0.14(0.10–0.19)

0.23(0.16–0.31)

 Stage 3 & 4

232/3381.9

6.86

 

1

Baseline CD4 cells/μl

    

 ≤200

211/4169.9

5.06

2.89(2.21–3.85)

1.36(1.02–1.84)

 >200

66/3771.4

1.75

  

Baseline weight in Kg

 ≤49

113/2646.4

4.27

1.88(1.12–3.43)

1.63(0.93–3.05)

 50–59

108/3343.7

3.23

1.42(0.85–2.59)

1.19(0.69–2.22)

 60–69

42/1333.3

3.15

1.39(0.78–2.64)

1.06(0.59–2.03)

 >69

14/616.7

2.27

1

1

Baseline OIs

 Yes

194/6278.3

3.09

0.62(0.48–0.80)

1.24(0.95–1.63)

 No

83/1660

5.00

1

1

CPT adherence

    

 Good

271/7765

3.49

0.99(0.48–2.51)

0.92(0.44–2.37)

 Fair, Poor & no CPT

2/56.8

3.52

1

1

  1. *others include: catholic, johoba and non belivers