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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: Detrimental role for CCAAT/enhancer binding protein δ in blood-borne brain infection

Fig. 1

C/EBPδ is detrimental for the blood-brain barrier upon intravenous pneumococcal infection. c/ebpδ mRNA (a) in wild-type brain tissue at different time points after intravenous inoculation with S. pneumoniae. Bacterial outgrowth in whole blood (b), brain (c) and lung (d) of wild-type and C/EBPδ−/− 24 and 48 h after infection. Correlation analysis of cebpd mRNA expression and bacterial loads in the brain (e). Data are expressed as scatter dot plots with the median (n = 6 for controls; n = 30 at both t = 24 and t = 48 h post infection). * P < 0.05, ** P < 0.01, *** P < 0.001

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