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Table 2 Mutations in the rpoB, katG, pncA and embB genes with the associated MICs and genotypes of the drug susceptible isolates

From: Mechanisms of first-line antimicrobial resistance in multi-drug and extensively drug resistant strains of Mycobacterium tuberculosis in KwaZulu-Natal, South Africa

Isolate

Genotype

MIC (mg/L)

Mutation Profile

RIF

INH

EMB

rpoB

katG

pncA

embB

TF1538

Unique

1

≤0.125

2

-

-

-

-

TF1413

Beijing

1

16

2

-

G1388T

-

-

TF1582

Beijing

1

≤0.125

2

-

G1388T

-

-

TF832

F11V

1

≤0.125

2

-

-

-

-

TF1519

Beijing

1

≤0.125

2

-

-

-

-

TF1001

Unique

1

≤0.125

2

-

-

-

-

TF933

Unique

1

≤0.125

2

-

-

-

-

P090811

Beijing

1

≤0.125

2

-

G1388T

-

-

P090802

Beijing

1

≤0.125

2

-

G1388T

-

-

P090804

Beijing

1

≤0.125

2

-

G1388T

-

-

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BMC Infectious Diseases

ISSN: 1471-2334

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