Table 1 Descriptive statistics

Median

(IQI)

Age (years)

59.0

(47.5 to 66.5)

SOFA

11

(8 to 13)

APACHE II

27

(20 to 36.5)

Mean heart rate (bpm)

103

(93 to 119)

MAP at up-titration (mmHg)

66

(61 to 72)

NEE infusion rate prior to intervention (μg/kg/min)

0.11

(0.02 to 0.28)

Number of interventions (normalized to 24 h)

12.2

(8.0 to 17.2)

Number of successful interventions (normalized to 24 h)

3.0

(1.3 to 4.8)

Ratio of successful interventions (normalized to 24 h)

0.28

(0.12 to 0.42)

Duration of NEE administration (hours)

22.8

(19.9 to 23.6)

Proportion

(n)

Female

52.6 %

(50)

MAP ≤ 65 at interventions (mmHg)

49.0 %

(472)

MAP ≤ 60 at interventions (mmHg)

23.0 %

(222)

Source of sepsis

 Pneumonia

32.6 %

(31)

 Abdominal

29.5 %

(28)

 Soft tissue

16.8 %

(16)

 Urinary

10.5 %

(10)

 Uncertain

3.2 %

(3)

 Bacteremia

2.1 %

(2)

 Joint

2.1 %

(2)

 Endocarditis

1.1 %

(1)

 Line infection

1.1 %

(1)

 Other

1.1 %

(1)