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Table 1 Literature reports of CNS infections caused by Mycoplasma hominis in non-neonatal patients (1950-2016.7)

From: Meningitis in a Chinese adult patient caused by Mycoplasma hominis: a rare infection and literature review

No.

Author & year

Pt age(years), sex

Pt Country

HU

Tr

SI

Clinical manifestation

Days to Dx after Ad

Dx basis

Antibiotics used prior to diagnosis

Final antibiotic regimen

Otc

Ref

1

Paine et al. [14]

20, M

USA

N

Y

Y

fever, headache, a stiff neck

18

C

S + P + St

Sm

CR

[14]

2

Payan et al. [15]

29, M

USA

Y

Y

Y

fever, loss of consciousness

23

C

O + Cp + N + C

T + E

CR

[15]

3

Madoff S et al. [16]

11, F

USA

N

N

Y

fever

26

GIT + IRT

V + E

Mc

De

[16]

4

McMahon et al. [24]

76, M

USA

N

N

Y

fever, unresponsive

18

C

P + G

none

De

[24]

5

Kersten RC et al. [17]

20, M

USA

Y

Y

Y

fever, comatose

19

C

A + M + Su + V + Cf

M + Cf + Az + Am + Cl

Re

[17]

       

NM

35

C

Az + Am + Cl

M + Cf + D + Cd

CR

[17]

6

Cohen & Kubak. [25]

18, F

USA

N

Y

Y

fever, altered mental status

20

C

E

D + Ci + C

CR

[25]

7

Zheng et al. [18]

22, F

USA

N

N

Y

fever, left-sided weakness and numbness

18

IRT + IBA

Ct + N + Ca + M

none

CR

[19]

8

Douglas et al. [19]

17, F

Australia

N

Y

Y

fever, headache, photophobia, nausea, vomiting

13

C + 16S

A + Ca + E

D + Cd

CR

[19]

9

House P et al. [20]

40, F

Spain

N

N

Y

headache, left facial weakness, nausea, afebrile

12 + “several”

C + 16S

V + Cf + M

Ci + M

CR

[20]

10

Kupila L et al. [21]

40, M

Finland

N

Y

Y

haematuria and urine retention, confused

14

16S

none

T

CR

[21]

11

McCarthy & Looke. [3]

48, M

Australia

N

N

Y

fever

36

C + 16S

Cz + V

Ga + Cd

CR

[3]

12

McCarthy & Looke. [3]

17, F

Australia

N

Y

Y

fever

17

C

V + Me

Ga + Mo

CR

[3]

13

Al Masalma et al. [22]

41, F

Russia

N

N

Y

vertigo, coma headache, hemiparesis

10

16S

V + Me

D

CR

[22]

14

Lee et al. [8]

48, F

Netherlands

Y

Y

Y

fever

15

16S

F + V

Mo

CR

[8]

15

Henao-Martínez et al. [10]

40, M

Somalia

N

Y

Y

fever

17

C + 16S

V + PT + Ct + M

D

CR

[10]

16

Pailhorie ‘s et al. [23]

43, M

France

N

Y

Y

fever, delirium tremens

13

Vitek MS + 16S

Me + V + Fo

L + D

CR

[23]

17

Whitson WJ [2]

17, M

USA

Y

Y

Y

fever, bicep and deltoid weakness

32

C

PT + V + Ct + M

D + Mo

CR

[2]

18

Hos NJ [27]

21, F

Germany

N

N

Y

fever, neck pain, nausea, vomiting,

31

C + 16S

A + Ct

Mo

CR

[27]

19

Reissier S [26]

39, M

France

N

Y

Y

afbrile, loss of consciousness

33

C + 16S + RT-PCR

PT + Li + Ct + Me + V

Mo

De

[26]

20

Present study

79, M

China

N

N

Y

fever, anepia and right-sided weakness

17

16S

Me + V + CF

Az + D + Mi

CR

 
  1. Ad admitted, C culture, CR clinical recovery, De death, Dx diagnosis, GIT growth inhibition test, HU hormone use, IBA immunoblot assay, IRT immunofluo-rescence test, Otc outcome, Re recurrence, Ref reference, SI surgical intervention, 16S 16S rDNA sequencing, RT-PCR real-time PCR, Tr trauma, yrs: years
  2. Ampicillin, (A) amoxicillin, (Am) azithromycin, (Az) chloramphenicol, (C) cefazolin, (Ca) clindamycin, (Cd) cefotaxime, (Cf) ciprofloxacin, (Ci) clavulanate potassium, (Cl) cephalothin (Cp), ceftriaxone (Ct), ceftazidime (Cz), cefoperazone/ sulbactam (CF), doxycycline (D), erythromycin (E),flucloxacillin (F), fosfomycin (Fo),gentamicin (G), gatifloxacin (Ga),levofloxacin (L), linezolid (Li), metronidazole (M), methacycline (Mc), meropenem (Me), minocyline (Mi), moxifloxacin (Mo),nafcillin (N), oxacillin (O),penicillin (P), piperacillin/tazobactam (PT), sulfadiazine (S), streptomycin (Sm), sulfathiazole (St), sulbactam (Su), tetracycline (T), vancomycin (V)