Table 1 Patients’ characteristics with bacteremia due to Moraxella catarrhalis, Streptococcus pneumoniae and Haemophilus influenzae

Age (months, mean ± SD)

16 ± 12

35 ± 32

25 ± 33

-

-

Gender (female, %)

6 (75 %)

51 (46 %)

6 (27 %)

0.153

0.188

 mean ± SD

8.31 ± 2.80

12.49 ± 6.15

10.20 ± 3.10

0.016^a

0.188

 IQR

7.45-9.25

8.70-13.60

8.30-10.88

  YES (n, %)

6 (75 %)

25 (23 %)

1 (5 %)

0.004^a

<0.001^a

  YES (n, %)

0 (0 %)

1 (1 %)

0 (0 %)

N/A

N/A

  YES (n, %)

5 (63 %)

32 (29 %)

2 (9 %)

0.106

0.007^a

  YES (n, %)

7 (88 %)

39 (35 %)

9 (41 %)

0.005^a

0.039^a

  YES (n, %)

1 (13 %)

14 (13 %)

1 (5 %)

1.000

0.469

  YES (n, %)

2 (25 %)

7 (6 %)

0 (0 %)

0.114

0.064

  YES (n, %)

6 (75 %)

18 (16 %)

0 (0 %)

0.001^a

<0.001^a

  YES (n, %)

5 (63 %)

7 (6 %)

0 (0 %)

<0.001^a

<0.001^a

  YES (n, %)

5 (63 %)

32 (29 %)

4 (18 %)

0.106

0.032^a

  YES (n, %)

2 (25 %)

45 (41 %)

10 (45 %)

0.472

0.419

  YES (n, %)

0 (0 %)

38 (38 %)

10 (45 %)

0.049^a

0.029^a

  YES (n, %)

6 (75 %)

18 (16 %)

1 (5 %)

0.001^a

<0.001^a

 Rhinorrhea (n, %)

2 (25 %)

53 (48 %)

3 (14 %)

0.281

0.589

 Cough (n, %)

5 (63 %)

44 (40 %)

5 (23 %)

0.274

0.078

 Convulsion (n, %)

1 (13 %)

31 (28 %)

8 (36 %)

0.445

0.374

 Vomiting (n, %)

2 (25 %)

14 (13 %)

1 (5 %)

0.296

0.166

 Diarrhea (n, %)

1 (13 %)

6 (5 %)

2 (9 %)

0.350

1.000

 Tmax (°C, mean)

38.9

39.3

39.0

0.176

0.557

 IQR

38.6–39.2

38.7–40.0

38.5–39.8

 Occult bacteremia

0 (0 %)

40 (36 %)

2 (10 %)

0.050

1.000

 Pneumonia

4 (50 %)

19 (17 %)

5 (22 %)

0.046

0.195

 Meningitis

0 (0 %)

4 (4 %)

8 (36 %)

1.000

0.071

 Otitis media/Sinusitis

0 (0 %)

13 (12 %)

1 (5 %)

0.596

1.000

 Others

3^b(38 %)

10^c(9 %)

5^d(22 %)

0.048

0.643

 Unknown

1 (12 %)

24 (22 %)

1 (5 %)

1.000

0.469

 Aminopenicillins^f

0 (0 %)

19 (17 %)

0 (0 %)

0.351

N/A

 Beta-lactam/Beta-lactamase inhibitor combinations^g

3 (38 %)

8 (7 %)

1 (5 %)

0.026

0.048

 Second generation cephalosporins^h

1 (12 %)

2 (2 %)

0 (0 %)

0.191

0.267

 Third generation cephalosporinsⁱ

3 (38 %)

71 (65 %)

17 (77 %)

0.147

0.078

 Others^j

1 (12 %)

17 (15 %)

8 (36 %)

1.000

0.374

 No treatment

0 (0 %)

3 (3 %)

2 (9 %)

1.000

1.000

 Initiation with combination therapy

0 (0 %)

10 (9 %)

6 (27 %)

1.000

0.155

Duration of fever after treatment (days, mean ± SD)

2.63 ± 0.92

1.86 ± 1.00

3.77 ± 3.61

0.012^a

0.599

 IQR

2–3

1–2

2–4.75

WBC (/μL, mean ± SD)

14,774 ± 13,750

19,706 ± 7862

17,805 ± 10,173

 IQR

9395–12,158

14,548–24,318

9468–22,988

0.011^a

0.277

ANC (/μL, mean ± SD)

11,395 ± 13,884

14,690 ± 7569

12,057 ± 7662

 IQR

5220–9049

8984–19,408

6964–15,575

0.025^a

0.237

CRP (mg/dL, mean ± SD)

1.86 ± 1.47

5.65 ± 6.68

8.09 ± 8.60

 IQR

1.00–2.68

1.00–8.03

1.30–15.08

0.114

0.091

 YES (n, %)

7 (88 %)

84 (76 %)

14 (64 %)

0.680

0.374

 YES (n, %)

2 (25 %)

9 (8 %)

1 (5 %)

0.162

0.166