From: Role of oral Minocycline in acute encephalitis syndrome in India – a randomized controlled trial
Outcome | Drug (140) | Placebo (141) | P | ||
---|---|---|---|---|---|
N/Mean | %/SD | N/Mean | %/SD | ||
Discharged2 | 92 | 65 · 7 | 90 | 63 · 8 | 0 · 740 |
Absconded2 | 3 | 2 · 1 | 3 | 2 · 1 | 0 · 992 |
LAMA2 | 14 | 10 · 0 | 22 | 15 · 6 | 0 · 159 |
Death in hospital2 | 31 | 22 · 1 | 26 | 18 · 4 | 0 · 440 |
Mean days to become afebrile1 | 3 · 63 | 2 · 94 | 3.72 | 2 · 53 | 0 · 926 |
Mean days to become convulsion free1 | 1 · 35 | 1 · 14 | 1.22 | 0 · 87 | 0 · 411 |
Mean days to full consciousness1 | 3 · 37 | 2 · 6 | 3.06 | 2 · 19 | 0 · 399 |
Mean days to oral feeds1 | 3 · 06 | 2 · 71 | 3 · 21 | 2 · 85 | 0 · 702 |
Mean days till discharge1 | 6 · 86 | 4 · 97 | 6 · 66 | 4 · 39 | 0 · 721 |
Glasgow Outcome scale at 3 months2 Normal/near normal Independent Dependent Vegetative Dead | 75 3 14 0 43 | 53 · 6 2 · 1 10 · 0 0.0 30 · 7 | 60 11 11 0 52 | 42 · 5 7 · 8 7 · 8 0.0 36 · 9 | Chi Square = 7 · 44 P = 0 · 059 |
3 month GOS Unknown | 5 | 3 · 5 | 7 | 4 · 9 |