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Table 2 Clinical information for HAdV-B7 and HAdV-B3 infected children

From: Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012

 

HAdV-B7

HAdV-B3

Variables

Single infection

Coinfection

Single infection

Coinfection

(n = 30)

(n = 52)

(n = 15)

(n = 27)

Age (years)a

3.47 ± 3.08

1.20 ± 1.26

4.91 ± 4.63

2.62 ± 2.99

Male (%)

19 (63.3 %)

41 (56.2 %)

9 (60.0 %)

17 (63.0 %)

Symptoms and signs

    

Fever

29 (96.7 %)

51 (98.1 %)

15 (100 %)

24 (88.9 %)

T max (°C)

39.84 ± 0.71

39.50 ± 0.57

39.55 ± 0.53

39.78 ± 0.67

Duration of fever (days)b

22.07 ± 21.52

14.02 ± 6.36

9.73 ± 7.31

15.38 ± 14.36

Cough

30 (100 %)

52 (100 %)

15 (100 %)

26 (96.3 %)

Rhinorrhea

4 (13.3 %)

7 (13.5 %)

3 (20 %)

5 (18.5 %)

Wheezing

17 (56.7 %)

37 (71.2 %)

7 (46.7 %)

13 (48.1 %)

Swelling of tonsils

11 (36.7 %)

9 (17.3 %)

7 (46.7 %)

9 (33.3 %)

Rash

3 (10.0 %)

5 (9.6 %)

0

3 (11.1 %)

Vomitting

3 (10.0 %)

5 (9.6 %)

2 (13.3 %)

3 (11.1 %)

Diarrhea

9 (30.0 %)

13 (25.0 %)

1 (6.7 %)

7 (25.9 %)

Conjunctivitis

1 (3.3 %)

3 (5.8 %)

0

1 (3.7 %)

Dyspnea

13 (43.3 %)

26 (50.0 %)

4 (26.7 %)

9 (33.3 %)

ICU admission

6 (20.0 %)

7 (13.5 %)

0

2 (7.4 %)

Any underlying diseases

5 (16.7 %)

6 (11.5 %)

4 (26.7 %)

4 (14.8 %)

Treatment

    

Mechanical ventilation

8 (26.7 %)

19 (36.5%)

4 (26.7 %)

4 (14.8 %)

Coticosteriods

26 (86.7 %)

45 (86.5%)

12 (80.0 %)

24 (88.9 %)

Inhaled

16 (53.3 %)

29 (55.8%)

5 (33.3 %)

14 (51.9 %)

Intravenous

    

Immunoglobulinc

8 (26.7 %)

20 (38.5 %)

0

4 (14.8 %)

Length of hospital stay (days)

18.50 ± 12.87

22.44 ± 11.67

12.33 ± 4.95

16.89 ± 10.88

Laboratory findings

    

WBC (×109/L)

8.75 ± 4.63

9.96 ± 4.95

10.34 ± 5.23

10.87 ± 3.91

CRP (mg/L)

34.68 ± 42.70

33.95 ± 39.30

41.96 ± 36.84

31.54 ± 27.96

AST, median (IQR) (U/L)d

67 (38.8–100)

60 (38.3–94.3)

33 (27–45)

38 (26–51)

ALT, median (IQR) (U/L)e

20 (16–36)

25 (19–42.8)

15 (12–21)

17 (13–26)

LDH, median (IQR) (U/L)f

565 (341.8–1232.8)

470.5 (305.3–922.8)

297 (207–397)

311 (245–462)

CK, median (IQR) (U/L)

125.5 (48–499.8)

87 (45.5–187.5)

77 (46–99)

6 (43–115)

HBDH, median (IQR) (U/L)g

408 (242.8–803)

356.5 (225.9–647.5)

219 (162–313)

210 (199–374)

  1. ICU intensive care unit, WBC white blood cell, CRP C-reaction protein, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, CK creatinine kinase, HBDH hydroxybutyrate dehydrogenase, IQR interquartile range
  2. aIndependent-Samples T test: HAdV-B7 single infection vs HAdV-B7 coinfection, p = 0.001
  3. bIndependent-Samples T test: HAdV-B7 single infection vs HAdV-B3 single infection, p = 0.038
  4. cFisher exact test: HAdV-B7 single infection vs HAdV-B3 single infecion, p = 0.038
  5. dMann–Whitney U test: HAdV-B7 single infection vs HAdV-B3 single infection, p < 0.001
  6. eMann–Whitney U test: HAdV-B7 single infection vs HAdV-B3 single infection, p = 0.029
  7. fMann–Whitney U test: HAdV-B7 single infection vs HAdV-B3 single infection, p = 0.001
  8. gMann–Whitney U test: HAdV-B7 single infection vs HAdV-B3 single infection, p = 0.001
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BMC Infectious Diseases

ISSN: 1471-2334

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