Table 3 Model parameters for pharmacodynamics

C₅₀ (μg/L)

0.6

280

0.6

5

15

Asexual parasite maximum kill rate (1/day)

8.9

4.8

9.2

4.6

0

Gametocyte stage I-IIb maximum kill rate (1/day)

2.5

2.4

2.5

2.3

2.0

Gametocyte stage III-IV maximum kill rate (1/day)

1.5

0

1.5

0

5.0

Mature gametocyte maximum kill rate (1/day)

0.7

0

0.7

0

50.0

Hepatocyte stage maximum kill rate (1/day)

0

0

0

0

0