Table 1 Characteristics of patients with and without sputum SPCN during treatment
All | Sputum SPCN (+) | Sputum SPCN (−) | P value | |
|---|---|---|---|---|
N = 800 | N = 111 | N = 689 | ||
Basic data | ||||
Age (years) | 55 ± 20 | 54 ± 18 | 55 ± 21 | p = 0.784 |
Sex (male) | 564 (71) | 88 (79) | 476 (69) | p = 0.033 |
Body Weight (kgs) | 57 ± 11 | 56 ± 11 | 57 ± 11 | p = 0.332 |
Smoking | 311 (39) | 63 (57) | 248 (36) | p < 0.001 |
Alcohol consumption | 171 (21) | 35 (32) | 136 (20) | p = 0.008 |
Diabetes mellitus | 182 (23) | 38 (34) | 144 (21) | p = 0.003 |
HbA1C (%) | 9.8 ± 3.2 | 10.6 ± 2.8 | 9.6 ± 3.3 | p = 0.149 |
Chest-X ray findings | ||||
Cavity formation | 285 (36) | 72 (65) | 213 (31) | p < 0.001 |
Cavity > = 4 cm | 146 (18) | 47 (42) | 99 (14) | p < 0.001 |
Pleural effusion | 101 (13) | 15 (14) | 86 (12) | p = 0.759 |
Sputum acid-fast stain | p < 0.001 | |||
Negative | 376 (47) | 5 (5) | 371 (54) | |
1+ | 162 (20) | 32 (29) | 130 (19) | |
2+ | 106 (13) | 25 (23) | 81 (12) | |
3+ | 73 (9) | 18 (16) | 55 (8) | |
4+ | 83 (10) | 31 (28) | 52 (8) | |
Symptoms | ||||
Cough | 557 (70) | 83 (75) | 474 (69) | p = 0.354 |
Haemoptysis | 74 (9) | 12 (14) | 62 (9) | p = 0.727 |
Fever | 141 (18) | 21 (19) | 120 (17) | p = 0.893 |
Body weight loss (>5%) | 194 (24) | 32 (29) | 162 (24) | p = 0.468 |
Laboratory findings | ||||
WBC (cells/μl) | 8469 ± 6840 | 8758 ± 2772 | 8423 ± 7287 | p = 0.136 |
Hemoglobin (g/dL) | 13 ± 2 | 13 ± 2 | 13 ± 2 | p = 0.995 |
Albumin (mg/dL) | 3.7 ± 2.2 | 3.4 ± 0.6 | 3.8 ± 2.5 | p = 0.390 |
Creatinine (mg/dL) | 1.1 ± 0.8 | 1.09 ± 0.5 | 1.15 ± 0.8 | p = 0.450 |