Characteristic | Anti-HPV16 Atb a | Unadjusted OR (95% CI) | OR1 b(95% CI) | OR2 c(95% CI) | p-trend/p-nominal d | |
---|---|---|---|---|---|---|
-ve | +ve | |||||
All women | 2659 | 522 | ||||
Age | ||||||
30-39 | 410 | 122 | Ref. | n/a | Ref. | |
40-49 | 345 | 93 | 0.90 (0.66-1.22) | n/a | 0.93 (0.67-1.28) | <0.001 |
50-59 | 1469 | 259 | 0.59 (0.46-0.75) | n/a | 0.71 (0.54-0.92) | 0.003 |
60-64 | 435 | 48 | 0.37 (0.26-0.53) | n/a | 0.53 (0.36-0.78) | |
Smoking | ||||||
Never | 1626 | 241 | Ref. | Ref. | Ref. | |
Past | 781 | 206 | 1.77 (1.44-2.18) | 1.76 (1.43-2.16) | 1.18 (0.95-1.48) | n/ae |
Current | 252 | 75 | 2.00 (1.49-2.68) | 1.91 (1.43-2.57) | 1.16 (0.85-1.60) | 0.310 |
N o of children | ||||||
0 | 245 | 81 | Ref. | Ref. | Ref. | |
1 | 296 | 81 | 0.83 (0.58-1.18) | 0.82 (0.58-1.17) | 0.91 (0.63-1.31) | 0.146 |
2 | 1087 | 204 | 0.57 (0.43-0.76) | 0.60 (0.45-0.81) | 0.81 (0.59-1.10) | 0.823 |
≥3 | 1031 | 156 | 0.46 (0.34-0.62) | 0.51 (0.38-0.70) | 0.78 (0.56-1.07) | |
Age at sexual debut | ||||||
≥18 | 1609 | 255 | Ref. | Ref. | Ref. | |
17 | 392 | 94 | 1.51 (1.16-1.96) | 1.44 (1.11-1.87) | 0.95 (0.72-1.26) | |
16 | 370 | 82 | 1.40 (1.06-1.84) | 1.29 (0.98-1.70) | 0.79 (0.59-1.07) | 0.315 |
15 | 132 | 45 | 2.15 (1.50-3.09) | 1.89 (1.31-2.74) | 1.06 (0.71-1.57) | 0.408 |
<15 | 84 | 32 | 2.40 (1.57-3.69) | 2.13 (1.38-3.29) | 1.00 (0.63-1.58) | |
Prefer not to answer | 72 | 14 | 1.23 (0.68-2.21) | 1.24 (0.69-2.25) | 0.56 (0.29-1.12) | |
C. trachomatis diagnosis | ||||||
No | 2545 | 467 | Ref. | Ref. | Ref. | |
Yes | 87 | 46 | 2.88 (1.99-4.17) | 2.73 (1.88-3.97) | 1.89 (1.27-2.80) | n/ae |
Prefer not to answer | 27 | 9 | 1.81 (0.85-3.88) | 1.73 (0.80-3.72) | 1.21 (0.55-2.66) | 0.006 |
Partners in last 5y | ||||||
0-1 | 2457 | 427 | Ref. | Ref. | Ref. | |
2 | 86 | 48 | 3.20 (2.22-4.63) | 2.93 (2.02-4.25) | 2.18 (1.48-3.21) | 0.165 |
≥3 | 76 | 39 | 2.95 (1.98-4.39) | 2.47 (1.64-3.71) | 1.49 (0.97-2.29) | <0.001 |
Prefer not to answer | 40 | 8 | 1.15 (0.53-2.47) | 1.23 (0.57-2.65) | 0.77 (0.33-1.80) | |
Partners before the last 5y | ||||||
0-1 | 1240 | 74 | Ref. | Ref. | Ref. | |
2 | 249 | 45 | 3.12 (2.11-4.62) | 2.99 (2.01-4.44) | 2.92 (1.96-4.36) | <0.001 |
≥3 | 934 | 325 | 5.89 (4.51-7.69) | 5.45 (4.17-7.13) | 4.65 (3.48-6.22) | <0.001 |
Prefer not to answer | 236 | 78 | 5.79 (4.07-8.23) | 5.47 (3.86-7.76) | 5.88 (3.95-8.76) | |
Lifetime N o sex partners | ||||||
1 | 934 | 38 | Ref. | Ref. | Ref. | |
2 | 337 | 35 | 2.55 (1.59-4.11) | 2.46 (1.52-3.96) | 2.35 (1.45-3.80) | <0.001 |
≥3 | 1166 | 374 | 7.89 (5.59-11.14) | 7.30 (5.16-10.33) | 6.50 (4.53-9.34) | <0.001 |
Prefer not to answer | 222 | 75 | 8.34 (5.50-12.65) | 8.08 (5.32-12.27) | 8.08 (5.14-12.69) |