Table 3 Pneumococcal (Spn) carriage, 7-valent pneumococcal conjugate vaccine (7PCV) uptake, carriage of 7PCV and 23PPV types, recent antimicrobial use, and carriage of non-susceptible pneumococci in children 0 to 6 years of age, by region and year.
Region | Central Australia | Darwin Rural¥ | East Arnhem | Katherine West | ||||
|---|---|---|---|---|---|---|---|---|
Year | 2003 | 2005 | 2003 | 2005 | 2003 | 2005 | 2003 | 2005 |
No. communities | 11 | 2 | 6 | 6 | 7 | 4 | 5 | 5 |
No. children swabbed | 158 | 65 | 320 | 376 | 315 | 223 | 109 | 154 |
Percent children (95% Confidence Interval) | ||||||||
Spn positive | 83(77–89) | 86(78–95) | 79(75–84) | 67(62–72)* | 85(81–89) | 87(83–92) | 82(74–89) | 78(71–85) |
Vaccinated (> = 1 dose) | 96(93–99) | 97(93–101) | 88(84–91) | 96(94–98)* | 80(76–84) | 97(95–99)* | 89(83–95) | 94(90–98) |
Vaccinated (primary) | 85(79–90) | 83(74–92) | 79(75–84) | 87(84–90)* | 71(66–76) | 82(77–87)* | 70(61–78) | 82(76–89) |
Vaccinated (primary+23v) | 46(39–54) | 54(41–66) | 34(29–39) | 65(60–69)* | 30(24–34) | 59(52–65)* | 39(29–48) | 62(54–69)* |
7PCV-type positive | 10(5–14) | 12(4–21) | 15(11–19) | 9(6–12) | 10(7–13) | 10(6–14) | 6(2–11) | 3(0–5) |
Serotype in 23PPV not in 7PCV | 41(33–49) | 40(29–52) | 33(27–38) | 25(21–29) | 26(21–33) | 23(17–28) | 30(22–39) | 31(23–38) |
19A | 14(8–19) | 15(6–24) | 17(12–21) | 10(7–13) | 8(5–11) | 6(3–9) | 5(1–9) | 10(5–14) |
6A | 0.6(-1–2) | 3(-1–7) | 3(1–5) | 2(0–3) | 6(4–9) | 4(2–7) | 6(1–10) | 1(0–3) |
6C | 3(0–6) | 2(-2–5) | 4(2–7) | 3(1–5) | 6(3–8) | 7(3–10) | 2(-1–4) | 5(2–9) |
16F | 10(5–15) | 11(3–19) | 12(8–15) | 12(8–15) | 11(7–14) | 10(6–14) | 19(12–27) | 6(2–9)* |
Prescribed beta-lactam | 28(21–35) | 38(26–51) | 17(13–21) | 16(12–20) | 7(4–9) | 12(7–16) | 9(4–15) | 10(5–14) |
Penicillin non-susceptible (MIC ≥ 0.12 μg/mL) | 25(19–32) | 42(29–54) | 18(14–22) | 9(6–12)* | 14(10–18) | 16(11–21) | 13(6–19) | 13(8–18) |
Prescribed macrolide | 0 | 2(-2–5) | 3(1–5) | 13(9–16)* | 0 | 0 | 2(-1–4) | 2(0–4) |
Azithromycin resistant (MIC ≥ 2 μg/mL) | 9(4–12) | 22(11–32) | 3(1–5) | 5(3–8) | 3(1–4) | 3(1–5) | 11(5–17) | 5(1–8) |