MBL2and Hepatitis C Virus Infection among Injection Drug Users

BMC Infectious Diseases

Table 1 Common variants of MBL2 genotyped in the Urban Health Study

Variant	dbSNP Identifier	Secretor*	Amino Acid Change	Function
T-1964C	rs1031101
G-618C	rs11003125	H/L (aka -550)		H = high, L = low
G-289C	rs7096206	Y/X (aka -221)		Y = high, X = low
T-65C	rs7095891	Q/P (aka +4)
Ex1 C-34T	rs5030737	A/D (Codon 52)	R52C	D = low
Ex1 G-27A	rs1800450	A/B (Codon 54)	G54D	B = low
Ex1 G-18A	rs1800451	A/C (Codon 57)	G57E	C = low
IVS2 G-630A	rs4935046
IVS2 T-250C	rs1838066
IVS3 G-28C	rs930508
Ex4 C+5G	rs930507
Ex4 T-1483C	rs10082466
Ex4 G-1067A	rs10824792
Ex4 G-901A	rs2120132
Ex4 G-710A	rs2099902

NOTE: Six common variants form secretor haplotypes including -618, -289, -65, Ex1 -34, Ex1 -27, Ex1 – 18. Nomenclature for description of sequence variations is described in http://snp500cancer.nci.nih.gov/terms_snp_region.cfm

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