Mean age [years (range)] | 36 (20–60) |
Sex (n) | Â |
   Male | 65 |
   Female | 25 |
CD4-positive cells (cells/mm3) | Â |
   Mean | 149 |
   Median | 89 |
   Range | 1–405 |
Mean time since diagnosis [month (range)] | 24 (0.5–108) |
Pre-existing ARV therapy (n) | Â |
   Yes | 49 |
   No | 40 |
Mean duration of ARV therapy [month (range)] | 10 (0.3–60) |
Neurologically asymptomatic (n) | 19 |
Neurologically symptomatic (n) | 71 |
   HIV-associated dementia | 6 |
   Vacuolar myelopathy | 1 |
   Opportunistic CNS infections (43) |  |
   Toxoplasmosis | 19 |
   Cryptococcal meningitis | 15 |
   Tuberculosis meningitis | 3 |
   PML | 2 |
   Associations |  |
   Cryptococcal and tuberculous | 3 |
   Cryptococcal and toxoplasmosis | 1 |
   Cryptococcal and vacuolar myelopathy | 1 |
Other (stroke, brain abscess, neuropathy) | 4 |
Undetermined neurological diagnosis | 16 |