Table 2 Demographic data and severity of the underlying disease of analyzed patients (n = 22) with BSI due to ceftazidime-resistant P. aeruginosa strains: difference between PER-1-positive (PER-1-P-Pa) and ESBL-negative Pa (ESBL-N-Pa) isolates.a
Demographic and clinical parameters | PER-1-Pa | ESBL-N-Pa | P value b |
|---|---|---|---|
No. BSI-patients | 9 | 13 | - |
Male/Female | 7/2 | 11/2 | - |
Age, mean year ± SD | 58.0 ± 22.1 | 63.4 ± 17.7 | NS |
Patient location | Â | Â | Â |
   - Medical | 3 (33.3) | 7 (53.8) | NS |
   - Surgical | 0 (0.0) | 2 (15.4) | NS |
   - ICU | 6 (66.7) | 4 (30.8) | 0.10 |
McCabe & Jackson groups | Â | Â | Â |
   - Nonfatal | 6 (66.7) | 5 (38.5) | NS |
   - Ultimately fatal | 1 (11.1) | 5 (38.5) | NS |
   - Rapidly fatal | 2 (22.2) | 3 (23.1) | NS |
Charlson weighted index, mean ± SD | 2.9 ± 2.57 | 3.5 ± 2.6 | NS |
Previous hospitalizations (during the last 12 months) | 5 (55.6) | 9 (69.2) | NS |
Previous use of antibiotics (during the last 12 months) | 5 (55.6) | 7 (53.8) | NS |
Hospital-acquired BSI | 9 (100) | 9 (69.2) | 0.07 |
Mean length of hospital stay (MLHS), mean ± SD (days) | 69.3 ± 58.0 | 41.6 ± 35.3 | 0.09 |
   - MLHS before BSI diagnosis, mean ± SD (days) | 22.9 ± 8.0 | 17.1 ± 24.0 | NS |
   - MLHS after the BSI, mean ± SD (days) | 46.4 ± 57.5 | 24.4 ± 20.6 | 0.11 |
28-day mortality | 2 (22.2) | 1 (7.7) | NS |
Mortality attributable to BSI (within 7 days of onset) | 1 (11.1) | 0 (0.0) | NS |