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Table 2 Patient and radiographic characteristics in relationship to clubbing as defined by the phalangeal depth ratio in patients with smear positive pulmonary tuberculosis

From: Digital clubbing in tuberculosis – relationship to HIV infection, extent of disease and hypoalbuminemia

Characteristic

"Gold standard" measurement

p-Value

Odds Ratio (95% Confidence limits)

 

Clubbing (n = 60)

No Clubbing (n = 140)

  

Hypoalbuminemia (n = 48)

19

29

0.097

1.8 (0.9 – 3.7)

HIV Seropositive (n = 163)

50

113

0.662

1.2 (0.5 – 2.9)

Karnofsky score ≥ 70% (n = 108)

23

85

0.003

0.40 (0.2 – 0.8)

Karnofsky score less than 70% (n = 92)

37

55

0.003

2.5 (1.3 – 4.9)

Prior TB treatment history (n = 24)

12

12

0.023

2.7 (1.0 – 6.9)

Extent of disease on Chest Radiograph

    

Minimal Disease (n = 36)

10

26

0.747

0.9 (0.4 – 2.1)

Moderate Disease (n = 98)

28

70

0.666

0.9 (0.5 – 1.7)

Advanced Disease (n = 65)

21

44

0.621

1.2 (0.6 – 2.3)

Bilateral Lung disease (n = 164)

52

112

0.261

1.6 (0.7 – 4.2)

Cavitary Disease (n = 85)

27

58

0.640

1.2 (0.6 – 2.2)