|  |  | Disease Unset | ||
---|---|---|---|---|---|
 |  |  | Days after inoculation with LCM Virus | ||
 | Survival (days) | Weight loss (grams) | Decreased mobility | Convulsions | Hair disheveled |
Vehicle | Â | Â | Â | Â | Â |
Mouse #1* | <<1 | NA | 0 | NA | NA |
Mouse #2* | <<1 | NA | 0 | NA | NA |
Mouse #3* | <<1 | NA | 0 | NA | NA |
Mouse #4 | 6 | 1.5 | 4.5 | 5.5 | 4.5 |
Mouse #5 | 6 | 2 | 4.5 | 5.5 | 4.5 |
Mouse #6 | 7 | 2 | 5 | 6 | 5 |
Mouse #7 | 7 | 1.5 | 5 | 6 | 5 |
Mouse #8 | 7 | 2.5 | 5 | 6 | 5 |
Mouse #9 | 7 | 4.5 | 5 | 6 | 5 |
Mouse #10 | 7 | 4.5 | 5 | 6 | 5 |
Mouse #11 | 7 | 4.5 | 5 | 6 | 5 |
Mouse #12 | 8 | 2 | 6 | 7 | 6 |
Mouse #13 | 8 | 2.5 | 6 | 7 | 6 |
Mouse #14 | 8 | 1 | 6 | 7 | 6 |
Mouse #15 | 8 | 1.5 | 6 | 7 | 6 |
Mouse #16 | 8 | 2 | 6 | 7 | 6 |
Mouse #17 | 8 | 2 | 6 | 7 | 6 |
Mouse #18 | 7 | 1.5 | 5 | 6 | 5 |
Mouse #19 | 8 | 2 | 6 | 7 | 6 |
Mouse #20 | 8 | 1.5 | 6 | 7 | 6 |
PAP 0.25 mg/kg | Â | Â | Â | Â | Â |
Mouse #1 | <<1 | NA | NA | NA | NA |
Mouse #2 | <<1 | NA | NA | NA | NA |
Mouse #3 | 6 | 1 | 4.5 | 5.5 | 5 |
Mouse #4 | 7 | 1.5 | 5 | 6 | 5 |
Mouse #5 | 8 | 1.5 | 6 | 7 | 5.5 |
Mouse #6 | 21 | 0 | 10 | NO | NO |
Mouse #7 | 21 | 0 | 10 | NO | NO |
Mouse #8 | 21 | 0 | 10 | NO | NO |
Mouse #9 | 21 | 0 | 10 | NO | NO |
Mouse #10 | 21 | 0 | 10 | NO | NO |