Figure 11

The expression of both CD11b and CD18 is dramatically reduced following association of peritoneal macrophages with Leishmania in both assays (SI or SD). Percent of CD18 expressing macrophages before and after incubation with Leishmania (SD assay). Macrophages were incubated with or without Leishmania for one hour and stained with the appropriate antibody followed by analysis using flow cytometry as described in Materials and Methods. n = 4 animals, and * p < 0.05.