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Table 1 Clinical characteristics and comparison of the Ofloxacin & Rifampicin and Doxycycline & Rifampicin group

From: Ofloxacin plus Rifampicin versus Doxycycline plus Rifampicin in the treatment of brucellosis: a randomized clinical trial [ISRCTN11871179]

Clinical findings

Doxycycline & Rifampicin group (n = 14)

Ofloxacin & Rifampicin group (n = 15)

Age (years) (median-range)

29 (24–61)

35 (18–60)

Male/Female

11/3

13/2

Hepatomegaly (n)

7

9

Fever (n)

13

15

Arthralgia (n)

13

13

Headache (n)

10

11

Sweating (n)

12

10

Splenomegaly (n)

7

7

Diagnosis with culture (n)

4

3

Diagnosis with agglutination (n)

12

13

Adverse effects

  

- Diarrhea (n)

1

2

- Nausea and vomiting (n)

3

1

Complication (n)

2 Sacroileitis

1 Sacroileitis **

1 Orchitis

Relapse (n)

2

2 **

Duration of fever after starting treatment (mean ± SD) (hours)

106 ± 26

74 ± 30 *

  1. *p < 0.05. ** p > 0.05