| No Viremia (n = 165) | Viremia (n = 59) | pvaluea |
---|---|---|---|
Age (median with range, years) | 2.95 (0–14) | 2.12 (0–15) | 0.05 |
  ≤ 1 years old | 10 (6%) | 14 (24%) | <0.001 |
  > 1 years old | 155 (94%) | 45 (76%) |  |
Gender | Â | Â | 0.43 |
  Male | 106 (64%) | 34 (42%) |  |
  Female | 59 (36%) | 25 (58%) |  |
Skin rash | 155 (94%) | 58 (98%) | 0.30 |
Oral ulcer | 162 (98%) | 55 (93%) | 0.08 |
Fever b | 152 (92%) | 52 (88%) | 0.43 |
Duration of fever (mean ± SD, days) | 2.99 ± 1.85 | 2.38 ± 1.99 | 0.07 |
Clinical Severity (Grade 1 to 4) | Â | Â | Â |
Uncomplicated disease | 65 (39%) | 23 (39%) | 0.54d |
Complicated disease | 100 (61%) | 36 (61%) | Â |
Myoclonic jerk or aseptic meningitis | 72 (44%) | 29 (49%) | Â |
Severe CNS involvement without cardiopulmonary failure | 17 (10%) | 5 (8%) | Â |
Severe CNS involvement with cardiopulmonary failure | 11 (7%) | 2 (3%) | Â |
Sample day for PCR test c | Â | Â | Â |
  ≤ 3 days | 44 (27%) | 40 (68%) | <0.001 |
  > 3 days | 121 (73%) | 19 (32%) |  |
Viral load c (median with range, log 10 copies/mL) | |||
  ≤ 3 days |  | 3.68 (0.88 - 6.99) | 0.01 |
  > 3 days |  | 3.13 (1.56 – 4.20) |  |