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Table 1 Association of pathologic group and biofilm production by isolated H. influenzae strains

From: Non typable-Haemophilus influenzae biofilm formation and acute otitis media

Groups

Level of biofilm production

Comparison between groups *p value OR [95% CI]

 

Negative

Moderate

Strong

Moderate + Strong

Reference vs Group 1

Reference vs Group 2

Reference vs Group 3

Reference vs Group 4

Group MEF** n = 41

24 (58.5%)

8 (19.5%)

9 (22%)

17 (40.5%)

0.083

0.19

0.16

0.32

AOM treatment failure

    

2.16 [0.90;5.16]

1.78 [0.75;4.24]

1.86 [0.79;4.40]

0.64 [0.26;1.55]

NP group 1*** n = 43

17 (39.5%)

11 (25.6%)

15 (34.9%)

26 (60.5%)

 

0.66

0.73

0.006

Control (healthy children)

     

1.21 [0.51;2.86]

1.16 [0.49;2.73]

3.39 [1.41;8.15]

NP group 2*** n = 43

19 (44.2%)

18 (41.9%)

6 (13.9%)

24 (55.8%)

  

0.93

0.02

First AOM without conjunctivitis

      

0.96 [0.41;2.24]

2.8 [1.17;6.69]

NP group 3*** n = 45

19 (43.2%)

13 (29.5%)

12 (27.3%)

25 (56.8%)

   

0.015

Recurrent AOM without conjunctivitis

       

0.34 [0.14;0.82]

NP group 4*** n = 44

31 (68.9%)

9 (20%)

5 (11.1%)

14 (31.1.5%)

    

AOM with conjunctivitis

 
  1. OR, odds ratio; 95% CI, 95% confidence interval.
  2. *Risk for carrying (moderate + strong) an H. influenzae strain producing biofilm.
  3. **Strains isolated from MEF.
  4. ***Strains isolated from the nasopharynx.