From: The risk factors for tuberculosis in liver or kidney transplant recipients
Characteristics | No. (%) (n = 45) |
---|---|
Age, mean years ± SD | 37.9 ± 10.0 |
Gender, number of male/number of female | 34/11 |
Temperature of 39°C or greater | 15 (33.3) |
Primary kidney or liver disease, n (%) | Â |
 Glomerulonephritis | 33 (73.3) |
 Diabetes | 7 (15.6) |
 Adult polycystic disease | 1 (2.2) |
 Liver cirrhosis | 2 (4.4) |
 Other | 2 (4.4) |
Donor type, n (%) | Â |
 Cadaveric | 32 (71.1) |
 Living | 12 (26.7) |
 DCD | 1 (2.2) |
The type of transplantation, n (%) | Â |
 Liver | 2 (4.4) |
 Kidney | 43(95.6) |
 Two or more transplants | 4 (8.9) |
Immunosuppressive drugs, n (%) | Â |
 Methylprednisolone | 45 (100) |
 Prednisone | 45 (100) |
 Mycophenolate mofetil | 44 (97.8) |
 Tacrolimus | 34 (75.6) |
 Cyclosporine | 10 (22.2) |
 Sirolimus | 1 (2.2) |
 Antilymphocytic or antithymocytic agents | 7 (15.6) |
Time of TB diagnosis posttransplant, no. of cases (%) | Â |
 < 7 mo | 13 (28.9) |
 7th to 12th mo | 4 (8.9) |
 > 12 mo | 28 (62.2) |
Evidence of latent TB (No. of positive test/No. of patients tested) | 17 (37.8) |
 Untreated TB lesion in chest plain radiograph | 10/40 (25.0) |
 Preop PPD test positive | 10/36 (27.8) |
 Preop IGRA test positive | 1/4 (25.0) |
 Recent TB contact history | 1/45 (2.2) |
Type of TB, n (%) | Â |
 Pulmonary | 28 (62.2) |
 Extrapulmonary1 | 4 (8.9) |
 Disseminated | 13 (28.9) |
Diagnostic modalities (No. of positive test/No.of patients tested) | Â |
 Culture positive | 23/38 (60.5) |
 Smear positive | 15/36 (41.7) |
 PCR positive | 12/20 (60.0) |
 Pathology only | 3/3 (100.0) |
 IGRA positive | 6/30 (20.0) |
 PPD positive | 5/20 (25.0) |
Diabetes mellitus, n (%) | 7 (15.6) |
Rejection within 6Â months prior to TB, n (%) | 15 (33.3) |
CMV infection within 3Â months prior to TB | 18 (40) |
HCV, HBV | 10 (22.2) |
Major infection within 3Â months prior to TB | 13 (28.9) |
ESR at the onset of TB > 40 mm/h | 18 (40.0) |
Creatinine at the onset of TB > 2 mg/dl | 10 (22.2) |
Crude mortality | 4 (8.9) |