Table 1 Demographic and clinical characteristics (number [percent]) of the study population by year, ANRS CO3 Aquitaine and IPEC/FIOCRUZ cohorts combined
2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | |
|---|---|---|---|---|---|---|---|---|---|
Number of patients | 3911 | 4165 | 4375 | 4568 | 4898 | 5267 | 5621 | 5916 | 6144 |
Age in yearsa | |||||||||
< 30 | 430 (11.0) | 419 (10.1) | 364 (8.3) | 336 (7.4) | 325 (6.6) | 384 (7.3) | 426 (7.6) | 456 (7.7) | 483 (7.9) |
30-39 | 1830 (46.8) | 1808 (43.4) | 1787 (40.8) | 1690 (37) | 1614 (33) | 1563 (29.7) | 1501 (26.7) | 1494 (25.3) | 1462 (23.8) |
40-49 | 1127 (28.8) | 1316 (31.6) | 1505 (34.4) | 1715 (37.5) | 1987 (40.6) | 2183 (41.4) | 2422 (43.1) | 2547 (43.1) | 2603 (42.4) |
50-59 | 359 (9.2) | 435 (10.4) | 518 (11.8) | 597 (13.1) | 700 (14.3) | 811 (15.4) | 905 (16.1) | 982 (16.6) | 1093 (17.8) |
> = 60 | 165 (4.2) | 187 (4.5) | 201 (4.6) | 230 (5) | 272 (5.6) | 326 (6.2) | 367 (6.5) | 437 (7.4) | 503 (8.2) |
Gender | |||||||||
Male | 2725 (69.7) | 2879 (69.1) | 3039 (69.5) | 3175 (69.5) | 3418 (69.8) | 3679 (69.9) | 3898 (69.3) | 4096 (69.2) | 4256 (69.3) |
Mode of HIV transmissionb | |||||||||
Heterosexual | 1129 (28.9) | 1274 (30.6) | 1371 (31.3) | 1464 (32) | 1613 (32.9) | 1798 (34.1) | 1994 (35.5) | 2176 (36.8) | 2328 (37.9) |
MSM | 1383 (35.4) | 1471 (35.3) | 1575 (36) | 1682 (36.8) | 1817 (37.1) | 1963 (37.3) | 2102 (37.4) | 2221 (37.5) | 2320 (37.8) |
IDU | 1011 (25.9) | 996 (23.9) | 984 (22.5) | 955 (20.9) | 965 (19.7) | 947 (18) | 933 (16.6) | 909 (15.4) | 858 (14) |
Other | 145 (3.7) | 150 (3.6) | 151 (3.5) | 155 (3.4) | 155 (3.2) | 157 (3) | 165 (2.9) | 161 (2.7) | 166 (2.7) |
Unknown | 243 (6.2) | 274 (6.6) | 294 (6.7) | 312 (6.8) | 348 (7.1) | 402 (7.6) | 427 (7.6) | 449 (7.6) | 472 (7.7) |
CD4 cell countc | |||||||||
> 500 | 1306 (38.3) | 1412 (39.5) | 1580 (41) | 1646 (41.9) | 1768 (40.7) | 1996 (41.9) | 2274 (44.9) | 2457 (45.3) | 2720 (47.2) |
351-500 | 787 (23.1) | 866 (24.2) | 920 (23.9) | 924 (23.5) | 1075 (24.7) | 1167 (24.5) | 1225 (24.2) | 1375 (25.4) | 1453 (25.2) |
201-350 | 777 (22.8) | 783 (21.9) | 795 (20.6) | 852 (21.7) | 931 (21.4) | 963 (20.2) | 997 (19.7) | 985 (18.2) | 1017 (17.7) |
51-200 | 427 (12.5) | 410 (11.5) | 449 (11.7) | 414 (10.5) | 446 (10.3) | 502 (10.5) | 459 (9.1) | 501 (9.2) | 479 (8.3) |
<= 50 | 114 (3.3) | 107 (3) | 107 (2.8) | 94 (2.4) | 128 (2.9) | 132 (2.8) | 115 (2.3) | 103 (1.9) | 93 (1.6) |
Plasma HIV RNAc | |||||||||
<= 400 | 1151 (33.8) | 1324 (37.3) | 1628 (42.3) | 1859 (47.3) | 2100 (48.8) | 2514 (53.5) | 2908 (58.5) | 3348 (63.1) | 3898 (68.4) |
401-3000 | 749 (22) | 795 (22.4) | 689 (17.9) | 598 (15.2) | 613 (14.3) | 604 (12.8) | 557 (11.2) | 511 (9.6) | 518 (9.1) |
3001-10000 | 475 (13.9) | 451 (12.7) | 445 (11.6) | 409 (10.4) | 393 (9.1) | 396 (8.4) | 345 (6.9) | 354 (6.7) | 318 (5.6) |
10001-100000 | 725 (21.3) | 716 (20.2) | 781 (20.3) | 789 (20.1) | 871 (20.3) | 862 (18.3) | 787 (15.8) | 805 (15.2) | 721 (12.6) |
> 100000 | 308 (9) | 267 (7.5) | 306 (8) | 277 (7) | 323 (7.5) | 325 (6.9) | 378 (7.6) | 288 (5.4) | 246 (4.3) |
≤ 1 year since first HIV + testd | |||||||||
Yes | 439 (11.2) | 350 (8.4) | 337 (7.7) | 316 (6.9) | 316 (6.5) | 421 (8.0) | 493 (8.8) | 496 (8.4) | 501 (8.2) |
On cARTe | |||||||||
Yes | 3506 (89.6) | 3724 (89.4) | 3932 (89.9) | 4101 (89.8) | 4393 (89.7) | 4684 (88.9) | 4913 (87.4) | 5197 (87.8) | 5508 (89.6) |
Hepatitis Bf | |||||||||
Yes | 215 (6.1) | 235 (6.2) | 249 (6.2) | 258 (6.1) | 280 (6.2) | 305 (6.3) | 331 (6.4) | 348 (6.4) | 367 (6.6) |
Hepatitis Cg | |||||||||
Yes | 949 (26.7) | 968 (25.5) | 1013 (25.2) | 1022 (24.2) | 1027 (22.6) | 1008 (20.5) | 1018 (19.4) | 999 (18.2) | 978 (17.3) |