From: Serum activin A and B, and follistatin in critically ill patients with influenza A(H1N1) infection
 | Included H1N1 patients n = 29 | Other H1N1 patients ICUs n = 28 | P value |
---|---|---|---|
Age, years | 47 [39–56] | 49 [37–55] | 0.994 |
Gender, male | 20 (69%) | 17 (61%) | 0.514 |
Obstructive pulmonary disease | 9 (31%) | 8 (29%) | 0.839 |
Chronic cardiac insufficiency | 9 (31%) | 4 (14%) | 0.207 |
Ischemic cardiac disease | 9 (31%) | 0 | 1.000 |
Body mass index >35 kg/m2 | 11 (39%) | 4 (15%) | 0.070 |
SAPS II, points | 24 [20-32] | 29 [24–39] | 0.016 |
SOFA at 24 h, score | 3 [2-7] | 6 [3–8] | 0.042 |
SOFA maximum, score | 7 [3–9] | 6 [4–11] | 0.493 |
Time from symptoms to hospital admission, hours | 132 [54–188] | 72 [36–168] | 0.115 |
Time from hospital admission to ICU admission | 19 [12–33] | 19 [8–35] | 0.792 |
CRP (mg/L) at ICU admission | 73 [33–163] | 57 [26–199] | 0.965 |
PaO2/FiO2 (mmHg) at ICU admission | 135 [101–261] | 132 [110–299] | 0.492 |
PaO2/FiO2 (mmHg), lowest | 100 [76–134] | 111 [79–269] | 0.274 |
Number of infiltrated quadrants on X-ray at admission | 4 [2–4] | 2 [1–3] | 0.025 |
ALI or ARDS | 19 (66%) | 16 (57%) | 0.516 |
Corticosteroid treatment | 19 (66%) | 13 (46%) | 0.2923 |
Ventilatory support | Â | Â | 0.144 |
No | 3 (10%) | 6 (21%) | Â |
Non-invasive | 13 (45%) | 6 (21%) | Â |
Invasive | 13 (45%) | 16 (57%) | Â |
CPAP or PEEP (mmHg) at admission | 7 [5–12] | 7 [6–8] | 0.485 |
Length of ventilatory support, days | 4 [2–10] | 4 [0–9] | 0.485 |
ICU length of stay, days | 5 [2–10] | 3 [1–9] | 0.389 |
Hospital length of stay, days | 12 [7–16] | 11 [5–25] | 0.812 |
ICU mortality | 1 (83%) | 0 | 1.000 |
Hospital mortality | 1 (3%) | 2 (7%) | 0.611 |