Characteristics | Empiric n = 88 (%) | Directed n = 46 (%) | p value |
---|---|---|---|
Age [median (IQRa)]* | 81 (72.3,88) | 85.5 (69.8,93) | 0.35 |
Residence prior to admission | |||
Home | 15 (17) | 20 (43) | 0.004 |
SNF | 72 (82) | 26 (57) | 0.004 |
APACHE II score [mean, SDb]Y | 17.9 ± 6.9 | 13.1 ± 5.2 | <0.0001 |
PSI score [mean, SD]Y | 153.4 ± 36.82 | 131.3 ± 34.9 | 0.0011 |
Mechanical ventilation | 33 (38) | 14 (30) | 0.45 |
Duration of mechanical ventilation [median IQR]* | 3 (2,7) | 6 (2.5,20.75) | 0.064 |
Vasopressor use | 37 (42) | 8 (17) | 0.0041 |
Outcomes | |||
Time to reach clinical stability [median (IQR)]* | 7 (4,10) | 6 (3.5,11.5) | 0.47 |
Clinical response | 55 (63) | 35 (76) | 0.12 |
Mortality at 28 days | 24 (27) | 5 (11) | 0.029 |
Readmission within 30 days | 11 (17) | 7 (18) | 0.79 |
Length of hospital stay of survivors [median (IQR)]* | 10 (6,15) | 8.5 (7,14.3) | 0.50 |