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Table 2 Demographic characteristics of patients treated with rifampin or non-rifampin regimen

From: Factors predictive of treatment failure in staphylococcal prosthetic vascular graft infections: a prospective observational cohort study: impact of rifampin

Population, n = 84

NoRifampicin

Rifampicin

p

 

n = 39, (%)

n = 45, (%)

 

Age, mean ± SD

68.59 ± 11.23

62.02 ± 10.93

0.006

Diabetes mellitus

10 (40.0%)

15 (60.0%)

0.441

Body mass index, mean ± SD

25.31 ± 4.28

25.72 ± 4.61

0.676

Creatinine clearance <60 ml/min

70.33 ± 31.95

86.07 ± 34.68

0.035

Immunodepression

5 (33.3%)

10 (66.7%)

0.261

Chronic obstructive pulmonary disease

11 (50.0%)

11 (50.0%)

0.15

Coronary disease

24 (50.0%)

24 (50.0%)

0.448

Aortic aneurysm

16 (50.0%)

16 (50.0%)

0.606

Presumed PVGI

1 (12.5%)

7 (87.5%)

0.043

Definite PVGI

38 (50.0%)

38 (50.0%)

0.043

Early definite PVGI (<4 months)

24 (57.1%)

18 (42.9%)

0.049

Late definite PVGI (> 4 months)

14 (41.2%)

20 (58.8%)

0.426

Extracavitary PVGI

19 (50.0%)

19 (50.0%)

0.550

Fever > 38°C

26 (46.4%)

30 (53.6%)

0.865

Fissuration/disruption

2 (22.2%)

7 (77.8%)

0.125

False aneurysm

7 (63.6)

4 (36.4)

0.209

White blood cells count (G/l)

11410.7 ± 4463.2

10882.1 ± 4162.3

0.0645

Mean ± SD

Autologous vein

9 (75.0%)

3 (25.0%)

0.032

Arterial homo/allograft

9 (37.5%)

15 (62.5%)

0.299

New prosthesis

4 (50.0%)

4 (50.0%)

0.831

Debridement

2 (50.0%)

2 (50.0%)

0.883

Medical treatment (no surgery)

5 (38.5%)

8 (61.5%)

0.531

Adequate empirical antibiotherapy

37 (46.8%)

42 (53.2%)

0.766

New surgery

9 (36.0%)

16 (64.0%)

0.165

Admission to intensive care unit

22 (62.9%)

13 (37.1%)

0.010

Septic shock at initial presentation

8 (53.3%)

7 (46.7%)

0.554

Post-operative dialysis

3 (75.0%)

1 (25.0%)

0.240

Death related to PVGI

11 (78.6%)

3 (21.4%)

0.008