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Table 4 Comparison of BNP, NGAL, and PCT according to the in-hospital mortality

From: Diagnostic and prognostic utilities of multimarkers approach using procalcitonin, B-type natriuretic peptide, and neutrophil gelatinase-associated lipocalin in critically ill patients with suspected sepsis

 

Total (n = 340)

Clinical sepsis (n = 119)

PCT-based sepsis (n = 150)

Survivors (n = 288)

Non-survivors (n = 51)

Survivors (n = 82)

Non-survivors (n = 37)

Survivors (n = 117)

Non-survivors (n = 33)

BNP (pg/mL)

69 (46.7 – 101.0)

200* (159.1 – 280.2)

48.2 (13.4 – 143.1)

237.0† (165.2 – 356.7)

112.0 (63.8 – 157.5)

253.0‡ (181.2 – 519.2)

NGAL (ng/mL)

184 (159.1 – 222.7)

227 (161.4 – 444.9)

189 (108.6 – 304.7)

218 (143.5 – 375.1)

346 (281.9 – 490.6)

254 (145.5 – 519.5)

PCT (ng/mL)

0.27 (0.23 – 0.39)

0.93* (0.54 – 1.35)

0.76 (0.43 – 1.52)

0.93 (0.63 – 1.34)

NA

  1. * P = 0.0002 vs. survivors.
  2. † P = 0.0014 vs. survivors.
  3. ‡ P = 0.0054 vs. survivors.
  4. Data are expressed as median (95% confidence interval).
  5. BNP: B-type natriuretic peptide; NGAL: neutrophil gelatinase-associated lipocalin; PCT: procalcitonin; NA: not applicable.
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BMC Infectious Diseases

ISSN: 1471-2334

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