Figure 2From: Diagnostic and prognostic utilities of multimarkers approach using procalcitonin, B-type natriuretic peptide, and neutrophil gelatinase-associated lipocalin in critically ill patients with suspected sepsis Comparison of BNP and NGAL according to the subscores of SOFA score. (A) The BNP concentrations according to the cardiovascular subscore of SOFA score were: 245.5 (5 – 2,140) pg/mL; 43 (1 – 5,000) pg/mL; 223.9 (12.6 – 1,260) pg/mL; 245 (13.5 – 1,850) pg/mL; and 257 (10.1 – 609) pg/mL, respectively. The BNP concentration was significantly associated with the cardiovascular subscore of SOFA score (P < 0.0001). (B) The BNP concentrations according to the respiratory subscore of SOFA score were: 180 (35 – 1,240) pg/mL; 232.5 (5 – 1,370) pg/mL; 281 (5 – 2,140) pg/mL; 43 (5 – 3,070) pg/mL; and 46.6 (5 – 5,000) pg/mL, respectively. Although the BNP concentration was significantly different according to the respiratory subscore of SOFA score, there was no increasing tendency (P < 0.0001). (C) The BNP concentrations according to the renal subscore of SOFA score were: 43.7 (5 – 3,070) pg/mL; 147 (5 – 5,000) pg/mL; 266.5 (5 – 4,900) pg/mL; 211.5 (5 – 5,000) pg/mL; and 1,220 (19.4 – 3,170) pg/mL, respectively. The BNP concentration was significantly associated with the renal subscore of SOFA score (P < 0.0001). (D) The NGAL concentrations according to the renal subscore of SOFA score were: 137 (16 – 1,301) ng/mL; 234 (33 – 1,300) ng/mL; 612 (59 – 1,301) ng/mL; 1015.5 (127 – 1,300) ng/mL; and 1,300 (444 – 1,300) ng/mL, respectively. The NGAL concentration was significantly associated with the renal subscore of SOFA score (P < 0.0001). Abbreviations: BNP, B-type natriuretic peptide; NGAL, neutrophil gelatinase-associated lipocalin; SOFA, sepsis-related organ failure assessment.Back to article page