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Table 2 Discrepant results between HCVAg and HCV-RNA

From: HCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes

Case

Genotype

HCVAg

HCV-RNA

Log ratio

Notes

n

 

Fmol/L

IU/mLI

RNA/Ag

 

1

3a

6.71

0

na

Therapy 12 m, log ratio at T0 1.08, neg for both at 32 m

2

1a

11.21

0

na

Therapy 8 m, log ratio at T0 2.46

2

1a

139.96

0

na

Therapy 16 m, log ratio at T0 2.46

3

3a

7.32

<12

na

Therapy 12 m, log ratio at T0 2.34, log ratio at 8 m 2.92

4

3a

6.82

<12

na

Therapy 4 m, log ratio at T0 2.43

5

na

0.00

1142

na

Untreated, single specimen

6

3a

0.20

1807

na

Untreated, single specimen

7

4

0.54

3468

na

Untreated, single specimen

8

3a

1.89

4975

na

Untreated, single specimen

9

na

1.78

7939

na

Untreated, single specimen

10

3a

1.19

9206

na

Untreated, single specimen

11

1a

2.69

1598723

14.44

Untreated, single specimen

12

1c

3,972.47

2097

0.92

Untreated, single specimen

13

1a

7.92

105551

5.59

Untreated, single specimen

14

3a

8.83

40643

4.87

Untreated, single specimen

15

3a

18.96

698555

4.57

Untreated, single specimen

16

3a

31.20

7338172

4.57

Untreated, single specimen

  1. Five samples from four patients positive for HCVAg and negative for HCV-RNA, seven samples negative for HCVAg despite HCV-RNA levels higher than 1,000 UI/mL, five samples with a Log ratio between the two assays outside the expected range; na, not available; m, months.